Evidence map›Paper›PMID 42110913›Full record

ArticleFrontiers in genetics2026

Clinical outcomes of preimplantation genetic testing for structural rearrangements in couples with chromosomal inversions: a retrospective analysis.

Yutong Li, Yuezhi Keqie, Cuiting Peng, Han Chen, Jun Ren, Hong Yang, Zhushu Liu, Wei Fan, Shan Luo, Xuemei Zhang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yutong LiDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Yuezhi KeqieDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Cuiting PengDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Han ChenDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Jun RenDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Hong YangDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Zhushu LiuDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Wei FanKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.
Shan LuoKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.
Xuemei ZhangDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Ting HuDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Shanling LiuDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Xinlian ChenDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Fan ZhouDepartment of Medical Genetics Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromosomal inversion is one of the common types of chromosomal structural rearrangements. For couples with chromosomal inversions, the appropriate recommendations for preimplantation genetic testing (PGT) remain a subject of ongoing debate. This study retrospectively included couples who underwent PGT between January 2019 and December 2024. All included couples were classified into subgroups based on karyotyping analysis: PGT-INV (chromosomal inversion), PGT-PV (chromosomal polymorphic variation), PGT-A (normal karyotype), and PGT-SR (other balanced chromosomal rearrangements). The euploid rate of biopsied blastocysts did not differ significantly among the PGT-INV, PGT-PV, and PGT-A groups (

Indexed as

aneuploidyblastocystschromosomal inversiongenetic counselingpreimplantation genetic testing

Identifiers

PMID42110913
PMCPMC13153762

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.