Evidence map›Paper›PMID 42110834›Full record

ArticleTransplantation direct2026

Kidneys From Older Donors After Circulatory Death Plus Normothermic Regional Perfusion or Standard Rapid Retrieval Have Comparable Function in the Context of Ex Situ Oxygenated Hypothermic Machine Perfusion.

Emma F Van de Geijn, Martin B A Heemskerk, Madeleine C Van Dijk, Rutger M Van Rooden, Fenna J Van der Heijden, Femke H C De Goeij, Aiko P J De Vries, Ian P J Alwayn, Robert C Minnee, Dorottya K De Vries and 2 more

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Article in Transplantation direct, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Emma F Van de GeijnDepartment of Surgery, Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0009-0009-4784-0748
Martin B A HeemskerkDutch Transplant Foundation, Leiden, The Netherlands.
Madeleine C Van DijkDepartment of Surgery, Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.
Rutger M Van RoodenDepartment of Surgery, Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.
Fenna J Van der HeijdenDepartment of Surgery, Transplant Institute, Erasmus Medical Center, Rotterdam, The Netherlands.
Femke H C De GoeijDepartment of Surgery, Transplant Institute, Erasmus Medical Center, Rotterdam, The Netherlands.
Aiko P J De VriesDivision of Nephrology, Department of Medicine, Leiden Transplant Center Leiden University Medical Center, and Leiden University, Leiden, The Netherlands.
Ian P J AlwaynDepartment of Surgery, Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.
Robert C MinneeDepartment of Surgery, Transplant Institute, Erasmus Medical Center, Rotterdam, The Netherlands.
Dorottya K De VriesDepartment of Surgery, Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.
Jeroen De JongeDepartment of Surgery, Transplant Institute, Erasmus Medical Center, Rotterdam, The Netherlands.
Volkert A L HuurmanDepartment of Surgery, Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: With growing transplant waiting lists, more extended criteria donor organs are being accepted, requiring optimization of the organs to increase utilization. Abdominal normothermic regional perfusion (aNRP) benefits the outcomes of transplanted livers and pancreatic islets, but its effects on donor kidneys subsequently preserved with (oxygenated) hypothermic machine perfusion (HMPO Methods: From October 2018 until June 2023, we evaluated all ≥50 y cDCD kidneys retrieved using aNRP during a pilot implementation project and compared posttransplant outcomes of these donor kidneys to those of cDCD kidneys retrieved by standard rapid retrieval during the same period. All kidneys received HMPO Results: Data of 70 aNRP-preserved kidneys were compared with a control group of 124 kidneys. One year estimated glomerular filtration rate was comparable between groups (40.4 mL/min/1.73 m Conclusions: This study demonstrates that aNRP-preserved kidneys from cDCD donors aged 50 y and older had comparable outcomes to kidneys retrieved with standard rapid retrieval, in the context of HMPO

Identifiers

PMID42110834
PMCPMC13155496

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.