Evidence map›Paper›PMID 42110832›Full record

ArticleTransplantation direct2026

Patient-reported Opioid use and Pain Management After Living Kidney Donation.

Amanda Leonberg-Yoo, Kristin E Leonberg, Samir Abu Gazala, Sarah Hryzak, Robert R Redfield, Ronald F Parsons, Anish K Agarwal, M Kit Delgado, Daniel Lee, Jennifer Trofe

Abstract read
In one paragraph

Article in Transplantation direct, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amanda Leonberg-YooDepartment of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID https://orcid.org/0000-0001-9810-9298
Kristin E LeonbergTufts University Friedman School of Nutrition Science and Policy, Boston, MA.
Samir Abu GazalaDepartment of Surgery, University of Pennsylvania, Philadelphia, PA.
Sarah HryzakDepartment of Medicine, University of Pennsylvania, Philadelphia, PA.
Robert R RedfieldDepartment of Surgery, Division of Transplant, University of California, Irvine, Irvine, CA.
Ronald F ParsonsDepartment of Surgery, University of Pennsylvania, Philadelphia, PA.
Anish K AgarwalDepartment of Emergency Medicine, University of Pennsylvania, Philadelphia, PA.
M Kit DelgadoDepartment of Emergency Medicine, University of Pennsylvania, Philadelphia, PA.
Daniel LeeDivision of Urology, University of Pennsylvania, Philadelphia, PA.
Jennifer TrofeDepartment of Medicine, University of Pennsylvania, Philadelphia, PA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study evaluated donor-reported opioid use and pain management outcomes after living donor nephrectomy at a single center. Prospective data were collected through an automated text-messaging platform to assess postdischarge pain intensity, perceived pain control, and use of prescribed opioids for acute postoperative pain. Methods: This prospective study was conducted at a large academic health system in Pennsylvania. Eligible participants were adult living kidney donors (aged 18 y and older) who underwent donor nephrectomy between July 2021 and March 2023. Data were collected using an automated text-messaging system from hospital discharge through postoperative day 28. Results: Of the eligible participants, 75 (71%) consented to participate. Donors who consented to follow-up did not differ significantly from those who did not consent in terms of demographic or perioperative characteristics. Inpatient opioid use and discharge prescribing practices were similar across groups. Of participants who responded at each follow-up, the median (interquartile range) self-reported pain intensity on day 4 was 4.0 (3.0-5.0) and decreased to 1.0 (0.0-2.0) by day 21. The median (interquartile range) perceived pain control increased to 10.0 (9.0-10.0) by day 14, with 3 (8.1%) of participants reporting opioid use by this time. Conclusions: From a systems perspective, these findings underscore the need to recalibrate default discharge prescribing practices. Implementing standardized order sets and feedback mechanisms may reduce excess opioid supply while maintaining living kidney donor comfort.

Identifiers

PMID42110832
PMCPMC13155497

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.