Evidence map›Paper›PMID 42110777›Full record

ArticleACS omega2026

Chlorin e6-Based Photodynamic Therapy for Metastatic Melanoma: An

Aishat Adejoke Obalola, Heidi Abrahamse, Sathish Sundar Dhilip Kumar

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aishat Adejoke ObalolaLaser Research Centre, University of Johannesburg-Doornfontein Campus, Johannesburg 2028, Gauteng South Africa.
Heidi AbrahamseLaser Research Centre, University of Johannesburg-Doornfontein Campus, Johannesburg 2028, Gauteng South Africa.
Sathish Sundar Dhilip KumarLaser Research Centre, University of Johannesburg-Doornfontein Campus, Johannesburg 2028, Gauteng South Africa.ORCID https://orcid.org/0000-0001-6964-1138

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma, the most aggressive form of skin cancer, remains incurable despite advances in treatment. Therefore, the need for alternative treatment approaches remains high. Photodynamic therapy is a localized, noninvasive treatment method. A photosensitizer is a crucial component of photodynamic therapy (PDT), which generates cytotoxic reactive oxygen species to kill cancer cells. A second-generation photosensitizer with FDA approval that satisfies the necessary clinical requirements for PDT is Chlorin e6 (Ce6). It is well-known for its strong anticancer effects on various cancer types and for its significant capacity to produce reactive oxygen species (ROS). Ce6 has demonstrated significant therapeutic potential against various cancers, including refractory ovarian, lung, melanoma, and metastatic breast cancer. In this study, we investigated the

Identifiers

PMID42110777
PMCPMC13150655

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.