Evidence map›Paper›PMID 42110714›Full record

ArticleInternational journal of microbiology2026

Genomic Evolution of the Increasing Prevalent Carbapenem-Resistant Hypervirulent ST15

Shuaihua Fan, Pengcheng Du, Yunfei Tang, Huaiqing Qi, Chao Liu, Jun Guo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuaihua FanDepartment of Pulmonary and Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China, tsinghua.edu.cn.
Pengcheng DuMedical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China, ccmu.edu.cn.
Yunfei TangDepartment of Infectious Disease, Peking University Third Hospital, Beijing, China, puh3.net.cn.
Huaiqing QiDepartment of Pulmonary and Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China, tsinghua.edu.cn.
Chao LiuDepartment of Infectious Disease, Peking University Third Hospital, Beijing, China, puh3.net.cn.ORCID https://orcid.org/0000-0001-5886-4264
Jun GuoDepartment of Pulmonary and Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China, tsinghua.edu.cn.ORCID https://orcid.org/0000-0002-7374-2465

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: ST15 Methods: In this study, we collected 766 isolates of Kp from a tertiary hospital and 19,060 Kp genomes from the NCBI Assembly database. We analyzed the phylogenetic characteristics and profiles of hypervirulence-associated genes among ST15 genomes, as well as their associations with other sequence types (STs). Results: We observed that the hypervirulence-associated genes in the ST15 carbapenem-resistant Conclusion: Overall, the genetic diversity of hypervirulence-associated genes within ST15 CRKP isolates may enhance the ability to survive and spread globally, offering crucial evidence for clinical strategies aimed at managing this strain.

Indexed as

carbapenem resistancehypervirulentKlebsiella pneumoniaeST15virulence plasmid

Identifiers

PMID42110714
PMCPMC13156470

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.