Evidence map›Paper›PMID 42110710›Full record

ArticleInternational journal of heart failure2026

Right Ventricular Function and Mortality in Critically Ill Patients With Heart Failure and Cardiogenic Shock.

Kirsten M Lipps, Garima Dahiya, Maan Jokhadar, Courtney E Bennett, Dustin B Hillerson, Bradley W Ternus, Ruben J Crespo-Diaz, Jacob C Jentzer

Abstract read
In one paragraph

Article in International journal of heart failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kirsten M LippsDivision of Critical Care Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.ORCID https://orcid.org/0000-0001-8298-4776
Garima DahiyaDivision of Critical Care Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.ORCID https://orcid.org/0000-0003-1925-7722
Maan JokhadarDivision of Critical Care Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.ORCID https://orcid.org/0009-0009-0882-2133
Courtney E BennettDivision of Critical Care Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Dustin B HillersonDivision of Critical Care Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.ORCID https://orcid.org/0000-0002-9962-8855
Bradley W TernusDivision of Critical Care Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Ruben J Crespo-DiazDivision of Critical Care Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Jacob C JentzerDivision of Critical Care Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.ORCID https://orcid.org/0000-0002-6366-2859

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Right ventricular dysfunction (RVD) is associated with poor prognosis in patients with acute heart failure (HF), including cardiogenic shock (CS). We evaluated the association of RVD by transthoracic echocardiogram (TTE) with mortality in cardiac intensive care unit (CICU) patients with HF. Methods: We conducted a retrospective cohort of patients with HF admitted to the Mayo Clinic CICU (2007-2018) who had a TTE within one day of admission. TTE-derived global assessment of right ventricular (RV) function was graded on a semi-quantitative scale. Outcomes included in-hospital and one-year mortality. Results: Among 2,450 patients (median 71.6 years, 38.4% female, 91.2% White), 75.7% had RVD (36.9% moderate/severe RVD). Global assessment of RVD correlated with advanced Doppler hemodynamics. Short-term mortality increased according to RVD severity (adjusted odds ratio, 1.30 per degree of RVD; 95% confidence interval [CI], 1.15-1.47, p<0.001), with similar findings after stratification by left ventricular function and CS (25.2% of the cohort). One-year mortality increased with RVD severity (adjusted hazard ratio, 1.21 per degree of RVD; 95% CI, 1.14-1.28, p<0.001). Severe RVD was associated with 51.2% one-year mortality (median survival 9.9 months). Patients with moderate/severe RVD without CS had similar mortality to those with mild/no RVD with CS. Conclusions: RVD is common among CICU patients with acute HF, and TTE-derived global assessment of RV function correlates with advanced Doppler hemodynamics. RVD severity by global assessment is associated with higher short- and long-term mortality, highlighting the potential utility of point-of-care ultrasound for risk stratification in CICU patients.

Indexed as

Critical careEchocardiographyHemodynamics

Identifiers

PMID42110710
PMCPMC13150462

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.