Evidence map›Paper›PMID 42110605›Full record

ArticleArchives of medical science : AMS2026

Effectiveness of low-tube current for reducing radiation dose in cerebral computed tomography perfusion.

Tian-Hao Yang, Chao Tian, Le-Jun Fu, Song Jin

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Tian-Hao YangDepartment of Radiology, Tianjin Huanhu Hospital, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Tianjin, China.
Chao TianDepartment of Radiology, Tianjin Huanhu Hospital, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Tianjin, China.
Le-Jun FuDepartment of Radiology, Tianjin Huanhu Hospital, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Tianjin, China.
Song JinDepartment of Radiology, Tianjin Huanhu Hospital, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study aims to investigate the reduction of radiation dose in cerebral computed tomography (CT) perfusion by lower low-tube current. Material and methods: Two hundred patients, who underwent cerebral non-contrast CT and CT perfusion, were randomized to four groups according to tube current and contrast media (CM) concentration: group A (60 mAs, 320 mg I/ml), group B (60 mAs, 370 mg I/ml), group C (100 mAs, 320 mg I/ml), and group D (100 mAs, 370 mg I/ml). Among these four groups, the CT dose index (CTDIvol), dose length product (DLP) and effective dose (ED) were calculated. The quantitative image comparison included maximum enhancement, noise, signal-to-noise ratio (SNR), cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time (MTT) from five regions of interests (ROIs). Results: Ranging from 100 mAs to 60 mAs, groups A and B achieved 40% lower CTDIvol, DLP and ED, compared with groups C and D. Both the maximum enhancement and noise of all ROIs were higher in groups A and B than in groups C and D ( Conclusions: The reduction in tube current from 100 mAs to 60 mAs for cerebral CT perfusion led to a 40% reduction in radiation dose without sacrificing image quality.

Indexed as

CT perfusionimage qualityiodine delivery ratelow-tube currentradiation dose

Identifiers

PMID42110605
PMCPMC13154748

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