Evidence map›Paper›PMID 42110458›Full record

ArticleFrontiers in medicine2026

Correlation analysis between quantitative lung ultrasound parameters and pulmonary function in idiopathic pulmonary fibrosis: an observational study.

Ting Zhou, Xing He, Xueming Ju, Chun Zhang, Hui Fang, Yang Liu, Jiao Wang, Chunhong Yang, Lu Guo

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Ting Zhou *Department of Pulmonary and Critical Care Medicine, Chengdu Sixth People's Hospital, Chengdu, Sichuan, China.
Xing He *State Key Laboratory of Respiratory Health and Multimorbidity, Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Xueming JuDepartment of Ultrasound, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Chun ZhangDepartment of Pulmonary and Critical Care Medicine, Chengdu Sixth People's Hospital, Chengdu, Sichuan, China.
Hui FangDepartment of Pulmonary and Critical Care Medicine, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Yang LiuDepartment of Pulmonary and Critical Care Medicine, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Jiao WangDepartment of Pulmonary and Critical Care Medicine, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Chunhong YangDepartment of Pulmonary and Critical Care Medicine, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Lu GuoDepartment of Pulmonary and Critical Care Medicine, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease (ILD) with limited monitoring tools. Lung ultrasound (LUS) has emerged as a promising radiation-free alternative, but its clinical utility in IPF requires further validation. This study aimed to comprehensively evaluate the correlation between quantitative LUS parameters and established disease severity markers in IPF patients. Methods: An observational study was conducted in eligible IPF patients. Participants underwent comprehensive assessment including clinical questionnaires, pulmonary function tests, serum KL-6 measurement, high-resolution computed tomography (HRCT), and a standardized LUS protocol. Correlation and multiple linear regression analyses were performed to examine the relationships between LUS indices and conventional severity markers. Results: The analysis included 47 IPF patients stratified by DLCO% predicted (≥60% mild, <60% moderate-severe). The moderate-severe group showed significantly higher B-line counts, B-line scores, pleural scores, diaphragm thickness and lower diaphragm thickening fraction ( Conclusion: Quantitative LUS parameters show strong and consistent correlations with clinical, functional, serological, and radiographic markers of IPF severity. These findings support the potential utility of LUS as a comprehensive, non-invasive tool for multidimensional disease assessment in IPF patients.

Indexed as

B-linesdisease monitoringidiopathic pulmonary fibrosislung ultrasoundpulmonary function

Identifiers

PMID42110458
PMCPMC13149454

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