Evidence map›Paper›PMID 42110451›Full record

ArticleFrontiers in medicine2026

Ultrawidefield OCTA study for the impact of PPVP on the structure and blood flow of the retina and choroid.

Xida Liang, Jing Zeng, Ruiming Yang, Wanni Chen, Zhimeng Zhang, Junming Wang

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xida Liang *Ophthalmic Center, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Jing Zeng *Ophthalmic Center, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Ruiming YangOphthalmic Center, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Wanni ChenOphthalmic Center, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Zhimeng ZhangDepartment of ophthalmology, Guangzhou First People's Hospital, the Second Affiliated Hospital of South China University of Technoloty, Guangzhou, China.
Junming WangOphthalmic Center, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the association between the posterior precortical vitreous pocket (PPVP) and retinal morphological and blood flow parameters, with the aim of elucidating its potential pathophysiological significance. Methods: This prospective single-center study included 65 healthy subjects. PPVP was assessed using spectral-domain optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA). The associations between PPVP presence and macular retinal thickness, volume, and vessel density were analyzed. Results: PPVP was detected in 72.3% (47/65) of subjects. Compared with the PPVP-negative group, the PPVP-positive group showed significantly greater retinal thickness in the superior inner macula (362.91 ± 16.84 vs. 344.06 ± 15.59 μm, Conclusion: The presence of PPVP was significantly associated with localized retinal thickening, increased retinal volume, and enhanced retinal blood flow. These findings suggest that PPVP may influence the vitreoretinal interface through biomechanical or microcirculatory mechanisms. This study systematically characterizes the morphological and functional features associated with PPVP and may contribute to a better understanding of the physiological vitreoretinal interface, with potential implications for future research into related retinal disorders.

Indexed as

blood flowchoroidOCTAPPVPretina

Identifiers

PMID42110451
PMCPMC13152791

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