Evidence map›Paper›PMID 42110368›Full record

ArticleInternational journal of pharmaceutics: X2026

Taste-masked tilmicosin-loaded nanostructured lipid carriers at pilot scale for improved bioavailability and enhanced efficacy against

Jiahao Gong, Zedong Zhang, Xingxing Cheng, Dafeng Wang, Huixin Wang, Deshan Miao, Yuxi Yin, Yuzhen Silang, Zeng Luo, Xia Chen and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of pharmaceutics: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jiahao GongEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.
Zedong ZhangEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.
Xingxing ChengEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.
Dafeng WangEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.
Huixin WangEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.
Deshan MiaoShandong Lvzhou Animal Pharmaceutical Co., Ltd., 100 Yibo Road, Linyi 276401, China.
Yuxi YinShandong Lvzhou Animal Pharmaceutical Co., Ltd., 100 Yibo Road, Linyi 276401, China.
Yuzhen SilangInstitute of Grassland Science, Tibet Academy of Agriculture and Animal Husbandry Sciences, 130 Jinzhu West Road, Lhasa 850000, China.
Zeng LuoInstitute of Grassland Science, Tibet Academy of Agriculture and Animal Husbandry Sciences, 130 Jinzhu West Road, Lhasa 850000, China.
Xia ChenCollege of Animal Science and Technology, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.
Qian GaoEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.
Yawei QiuEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.
Xiuge GaoEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.
Junren ZhangEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.
Dawei GuoEngineering Center of Innovative Veterinary Drugs, Center for Veterinary Drug Research and Evaluation, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salmonellosis remains one of the most prevalent bacterial enteric diseases in swine production worldwide. Tilmicosin (TMS) is widely used in swine bacterial infections, but its oral application is limited by gastric degradation and intense bitterness, reducing bioavailability and therapeutic efficacy. This study aimed to develop and evaluate pilot-scale TMS-loaded nanostructured lipid carriers (TMS@NLCs) to overcome these obstacles. Herein, TMS@NLCs were fabricated at 100-L scale

Indexed as

BioavailabilityBitter-maskingNanostructured lipid carriersOral deliveryPilot scaleSalmonellaTilmicosin

Identifiers

PMID42110368
PMCPMC13156769

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.