ArticleFrontiers in oral health2026
Antibiotic resistance and biofilm forming capacity of supragingival bacteria in healthy and caries patients.
Article in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aim: The oral cavity represents a reservoir for antimicrobial resistance, and supragingival biofilms contribute to reduced antibiotic susceptibility. This study aimed to compare the antimicrobial susceptibility and biofilm-forming capacity of bacterial isolates obtained from dentally healthy individuals and participants with active carious lesions. Methods: A total of 319 bacterial isolates from 40 participants were tested for susceptibility to clinically relevant antibiotics using disk diffusion and Etest methods, supplemented by Results: Resistant isolates were detected across all examined taxa. Significant group differences were observed for Conclusion: Specific bacterial taxa showed distinct differences in antibiotic susceptibility and biofilm-forming capacity between caries and healthy participants. The findings indicate that supragingival biofilms from caries-active individuals may harbour altered resistance patterns, particularly among obligate anaerobic species. These isolate-level observations underscore the need to further investigate how caries-associated ecological shift in oral biofilms relate to antimicrobial resistance.
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