Evidence map›Paper›PMID 42110175›Full record

ReviewReviews in cardiovascular medicine2026

Advances in Diagnosis and Therapeutic Guidance for Acute Coronary Syndrome: A Narrative of A Precision Medicine Approach.

Takuma Koike, Tomiharu Niida, Seiji Koga, Kenji Yaginuma, Kikuo Isoda, Kenji Inoue

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Takuma KoikeDepartment of Cardiovascular Biology and Medicine, Juntendo University Nerima Hospital, 177-8521 Tokyo, Japan.ORCID https://orcid.org/0000-0001-6360-3181
Tomiharu NiidaDepartment of Cardiovascular Biology and Medicine, Juntendo University Nerima Hospital, 177-8521 Tokyo, Japan.ORCID https://orcid.org/0000-0001-9665-4102
Seiji KogaDepartment of Cardiovascular Biology and Medicine, Juntendo University Nerima Hospital, 177-8521 Tokyo, Japan.ORCID https://orcid.org/0000-0001-7726-0802
Kenji YaginumaDepartment of Cardiovascular Biology and Medicine, Juntendo University Nerima Hospital, 177-8521 Tokyo, Japan.
Kikuo IsodaDepartment of Cardiovascular Biology and Medicine, Juntendo University Nerima Hospital, 177-8521 Tokyo, Japan.
Kenji InoueTokyo Heart Rhythm Clinic Shinjuku, 151-0053 Tokyo, Japan.ORCID https://orcid.org/0000-0002-7193-8421

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute coronary syndrome (ACS) remains one of the leading causes of cardiovascular morbidity and mortality. Recent advances in high-sensitivity cardiac troponin assays, multimodal imaging, and antithrombotic therapies have introduced more individualized risk assessment and management. This review highlights a precision-oriented diagnostic pathway, which integrates the 0/1-hour algorithm with imaging modalities for the comprehensive evaluation of culprit and non-culprit lesions. Revascularization strategies are advancing, with imaging-guided percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG), enabling more tailored approaches for complex diseases. Meanwhile, mechanical circulatory support offers potential benefits for cardiogenic shock; nevertheless, there are uncertainties regarding optimal timing and patient selection. Long-term antithrombotic therapy is becoming increasingly optimized. Recent strategies have focused on reducing the duration of dual antiplatelet therapy (DAPT) and exploring de-escalation approaches such as P2Y

Indexed as

de-escalation therapydual antiplatelet therapyhigh-sensitivity troponinrevascularization strategyrisk stratificationuniversal definition of myocardial infarction

Identifiers

PMID42110175
PMCPMC13155989

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.