Evidence map›Paper›PMID 42110162›Full record

ReviewReviews in cardiovascular medicine2026

Pericardial Inflammatory Mediators in Patients Undergoing Cardiac Surgery: Towards a Biomarker-Informed Clinical Practice.

Michael Blackledge, Hamza Nasir Chatha, Angel Luis Fernández González, Yasir Abu-Omar, Adham Elsherbini, Mohammad El Diasty

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael BlackledgeSchool of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID https://orcid.org/0009-0003-8966-382X
Hamza Nasir ChathaSchool of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID https://orcid.org/0000-0002-5249-2321
Angel Luis Fernández GonzálezDivision of Cardiovascular Surgery, University Hospital, 15706 Santiago de Compostela, Spain.ORCID https://orcid.org/0000-0003-1307-8221
Yasir Abu-OmarSchool of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID https://orcid.org/0009-0005-0728-9884
Adham ElsherbiniFaculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.ORCID https://orcid.org/0000-0002-9966-0599
Mohammad El DiastySchool of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID https://orcid.org/0000-0002-1807-8397

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative atrial fibrillation, heart failure, and pericardial effusion remain frequent complications after cardiac surgery. Pericardial fluid is a localized inflammatory compartment in close contact with the myocardium and may provide information that complements systemic biomarkers. This narrative review summarizes inflammatory mediators identified in pericardial fluid after cardiac surgery and their associations with postoperative outcomes. We discuss potential mechanistic links between pericardial inflammation and pericardial fluid markers, as well as practical limitations related to sampling, timing, and standardization. Although pericardial fluid biomarkers may augment existing clinical risk models, prospective studies are needed to determine their incremental value and clarify their role in perioperative management.

Indexed as

inflammatory markerspericardial fluidpericardium

Identifiers

PMID42110162
PMCPMC13155999

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.