ArticleJPGN reports2026
Gastrointestinal strictures in a pediatric patient with Satoyoshi syndrome.
Article in JPGN reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
We present a novel case of gastrointestinal strictures in a young girl with Satoyoshi syndrome (SS), highlighting multi-system features of alopecia universalis, painful muscle cramps with dystonia, aberrant growth velocity, and skeletal abnormalities. This case demonstrates an unusual pattern of patchy mucosal fibrosis throughout the gastrointestinal tract, alongside duodenal and rectal strictures, with only mild inflammation. While serial endoscopic dilatations and systemic corticosteroids resulted in symptomatic benefit, trial of a Janus kinase-1 inhibitor (upadacitinib) did not prevent the development of a subsequent rectal stricture. As the pathogenesis of SS remains undefined and treatment modalities are experimental, the observed fibrostenotic complications may point towards new underlying disease mechanisms.
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