ArticleCureus2026
Vancomycin Re-Exposure-Induced Immune Hemolytic Anemia.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vancomycin-induced immune hemolytic anemia is a rare but potentially life-threatening adverse drug reaction that is often underrecognized. We report a case of a 76-year-old male who developed an infection following hip arthroplasty and received vancomycin for the first time in September 2025, resulting in a decrease in hemoglobin from 14.1 g/dL to 10.4 g/dL with normal platelet counts. After readministration in March 2026, hemoglobin decreased by 8.2 g/dL, reticulocyte count rose to 7.00%, and the direct antiglobulin test was positive, confirming drug-induced immune hemolytic anemia (DIIHA). Hemoglobin gradually recovered after discontinuation, but reactive thrombocytosis and coagulation abnormalities occurred. This case highlights that vancomycin can induce immune hemolytic anemia, with more severe and rapid progression upon re-exposure.
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