Evidence map›Paper›PMID 42110037›Full record

ArticleCureus2026

Post-Acute Sequelae of COVID-19 at 12 Months in Hospitalized Patients: A Colombian Cohort Study.

Alvaro J Lora Mantilla, Laura A Parra-Gómez, Valentina Ortegón-Vargas, Mariam Posso Paz, Catalina Cáceres Ramírez, Alberto J Vasquez-Cadena, Maria C Ayala-Gutierrez, Maria C Amaya Muñoz, Maria P Blanco Rueda, Maria I Diaz Caraballo and 3 more

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alvaro J Lora MantillaResearch Directorate, Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, COL.
Laura A Parra-GómezResearch Directorate, Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, COL.
Valentina Ortegón-VargasResearch Directorate, Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, COL.
Mariam Posso PazPathology, University of New Mexico, Albuquerque, USA.
Catalina Cáceres RamírezResearch Directorate, Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, COL.
Alberto J Vasquez-CadenaResearch Directorate, Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, COL.
Maria C Ayala-GutierrezResearch Directorate, Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, COL.
Maria C Amaya MuñozResearch Directorate, Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, COL.
Maria P Blanco RuedaInternal Medicine, Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, COL.
Maria I Diaz CaraballoMedicine, Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, COL.
Silvia J Villabona-FlorezResearch Directorate, Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, COL.
Edgar D Gomez LaittonInternal Medicine, Fundación Oftalmológica de Santander (FOSCAL), Bucaramanga, COL.
Paul A Camacho LopezResearch Directorate, Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, COL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesPost-acute sequelae of SARS-CoV-2 infection (PASC) are a major source of long-term morbidity among COVID-19 survivors, particularly after hospitalization. However, information on PASC prevalence and associated factors at 12 months in Latin America remains limited. This study aimed to estimate the prevalence of PASC at 12 months among hospitalized COVID-19 patients and to identify factors associated with its persistence.

methodsWe conducted an ambidirectional, single-center cohort study including adult patients hospitalized with laboratory-confirmed SARS-CoV-2 infection who completed follow-up evaluations at six and 12 months after discharge. PASC was defined according to the World Health Organization (WHO) criteria. Sociodemographic variables, comorbidities, markers of in-hospital disease severity, and follow-up information were collected using standardized protocols. Statistical analyses included descriptive and bivariate comparisons according to PASC status at 12 months.

resultsAmong 869 hospitalized COVID-19 survivors, the prevalence of PASC at 12 months was 40.7% (n=354). Female sex, markers of severe acute disease, and the presence of PASC at six months were significantly associated with PASC persistence at 12 months. Vaccination coverage at follow-up was high, and although adverse reactions to vaccination were more frequently reported among patients with PASC, no differences in PASC development were observed according to vaccine platform.

conclusionsMore than two out of five patients experienced PASC one year after hospitalization for COVID-19. Associations with severe acute disease and vaccine reactogenicity support the hypothesis that dysregulated host immune responses may contribute to persistent post-COVID symptoms, highlighting the need for early identification and longitudinal follow-up of high-risk patients.

Indexed as

cohort studycolombiapost-acute sequelae of covid-19post-acute sequelae of sars-cov-2 infection (pasc)sars-cov-2 complicationsvaccination

Identifiers

PMID42110037
PMCPMC13152677

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.