ArticleCureus2026
The Long Tail of Long COVID-19: Broad and Extensive Increase in Utilization Within an Integrated Healthcare System.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
Funding
Abstract
backgroundThe impact of the emergence of Long COVID on healthcare utilization in a U.S. community setting remains underexplored.
objectiveTo examine the healthcare utilization of Long COVID patients compared with pre-COVID-19 era controls before and after SARS-CoV-2 infection within a large integrated delivery system.
methodsThis was a retrospective cohort study of adult patients with documented SARS-CoV-2 infection (1/1/2021-6/30/2022) in a multi-site Northern California health system. Long COVID diagnosis was defined by at least one encounter with an associated International Classification of Diseases, Tenth Revision code and/or referral to Long COVID specialty care. Utilization outcomes included inpatient/outpatient encounters, laboratory/imaging/functional testing, specialty care referrals/encounters, and medication use. We used propensity-weighted difference-in-differences models adjusted for study month to compare outcomes between baseline and post-SARS-CoV-2 infection (Long COVID window). Results: Among 600,295 patients with 635,230 SARS-CoV-2 episodes, 3,545 met criteria for Long COVID care-seeking. Long COVID patients had higher baseline utilization and greater increases in post-diagnosis utilization in adjusted analyses. After propensity weighting, these differences persisted and were consistent across the study period, particularly in cardiac and pulmonary care. Total encounters per year were 29.9 post and 14.1 pre (Long COVID) versus 17.7 post and 12.5 pre (NO Long COVID). Total annual ED visits per 100 patients were 65.1 post and 38.0 pre (Long COVID) versus 38.0 post and 32.0 pre (NO Long COVID). Annual hospitalizations per 100 patients were 10.5 post and 5.3 pre (Long COVID) versus 7.4 post and 5.5 pre (NO Long COVID).
conclusionLong COVID patients had higher healthcare utilization before and after diagnosis, with sharper increases across nearly all outcomes.
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