ArticleCureus2026
A Diagnosis of Exclusion: Unraveling Adult-Onset Still's Disease.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adult-onset Still's disease (AOSD) is a rare systemic autoinflammatory disorder characterized by quotidian fevers, arthralgia, transient rash, and elevated inflammatory markers, often leading to diagnostic delay due to overlap with infectious, autoimmune, and malignant conditions. We present the case of a 60-year-old Latina woman who developed daily fevers, polyarthralgia, rash, and hypoxemic respiratory failure. Despite broad-spectrum antibiotics, her symptoms persisted, and extensive infectious and hematologic evaluations were unrevealing. A diagnosis of AOSD was established based on the Yamaguchi criteria and markedly elevated ferritin. The patient responded to corticosteroids but later developed macrophage activation syndrome (MAS), requiring anakinra in addition to high-dose steroids. This case highlights the diagnostic challenges of AOSD in older adults, the potential for atypical systemic manifestations such as pulmonary nodules and anasarca, and the importance of early cytokine-directed therapy to prevent life-threatening complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.