ArticleCureus2026
Charting the Uncharted: Clinico-Microbiological Profile of Bacteria Isolated From Bronchoalveolar Lavage Samples of Patients With Lower Respiratory Tract Infections at a Tertiary Care Hospital in Odisha, India.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and objectives Lower respiratory tract infections (LRTIs) are a major cause of morbidity and mortality worldwide, with growing diagnostic challenges due to evolving bacterial profiles and antimicrobial resistance. This study aimed to evaluate the clinico-microbiological spectrum of bacteria isolated from bronchoalveolar lavage (BAL) samples in patients with suspected LRTIs and to analyze their antimicrobial susceptibility patterns at a tertiary care hospital in Odisha, India. Methods A retrospective observational study was carried out over three years, during which BAL samples from adult hospitalized patients with clinically diagnosed LRTIs were processed using established microbiological techniques. Bacterial identification and antimicrobial susceptibility testing were performed following standard microbiological procedures. Demographic data and comorbidities were also evaluated. Results Of 390 BAL samples, 222 (56.9%) yielded significant pathogenic growth. A male predominance and a high prevalence of comorbidities, particularly diabetes mellitus, were noted among the patients. Gram-negative bacteria constituted the majority of isolates, with
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