ArticleiScience2026
Pulsed photobiomodulation reprograms the tumor immune microenvironment to restore local T cell-mediated antitumor immunity.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Developing strategies to precisely modulate the tumor immune microenvironment (TME) is crucial for advancing immunotherapy. Here, we reported that 980-nm pulsed photobiomodulation (PBM) inhibits early tumor growth by locally reinvigorating antitumor immunity, without direct cancer cell cytotoxicity. In syngeneic LLC and MC38 models, daily PBM delayed tumor growth and conferred durable protection upon rechallenge without systemic toxicity, while efficacy was dependent on CD8
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.