ArticleEFSA journal. European Food Safety Authority2015
Scientific Opinion on Dietary Reference Values for vitamin E as α-tocopherol.
Article in EFSA journal. European Food Safety Authority, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 7 of them syntheses that pooled it.
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141 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Overnutrition is a risk factor for iron, but not for zinc or vitamin A deficiency in children and young people: a systematic review and meta-analysis.BMJ global health · 2024Pooled it
- Vitamin E Intake and Risk of Prostate Cancer: A Meta-Analysis.Nutrients · 2022Pooled it
- Vitamin A Concentration in Human Milk: A Meta-Analysis.Nutrients · 2022Pooled it
- Vitamin D supplementation for term breastfed infants to prevent vitamin D deficiency and improve bone health.The Cochrane database of systematic reviews · 2020Pooled it
- Serum 25-hydroxyvitamin D response to vitamin D supplementation in infants: a systematic review and meta-analysis of clinical intervention trials.European journal of nutrition · 2020Pooled it
- Genetic Variants Shaping Inter-individual Differences in Response to Dietary Intakes-A Narrative Review of the Case of Vitamins.Frontiers in nutrition · 2020Pooled it
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- Higher Prevalence of Inadequate Vitamin D Intake in Toddlers Not Consuming a Vitamin D Supplement in Vancouver, Canada.The Journal of nutrition · 2026Trial
- Effects of vitamin D supplementation during autumn and winter on blood biomarkers and physical performance in runners and non runners.Scientific reports · 2026Trial
- Maternal vitamin A and D status in second and third trimester of pregnancy and bone mineral content in offspring at nine years of age.Frontiers in endocrinology · 2024Trial
- 25-OHD response to vitamin D supplementation in children: effect of dose but not GC haplotype.European journal of endocrinology · 2021Trial
- Patisiran Pharmacokinetics, Pharmacodynamics, and Exposure-Response Analyses in the Phase 3 APOLLO Trial in Patients With Hereditary Transthyretin-Mediated (hATTR) Amyloidosis.Journal of clinical pharmacology · 2020Trial
- Outcome of Combined Neoadjuvant Chemotherapy and Vitamin A in Advanced Cervical Carcinoma: A Randomized Double-Blind Clinical Trial.Asian Pacific journal of cancer prevention : APJCP · 2019Trial
- An overview of international reference values for vitamin E intake - similarities and differences in derivation.European journal of nutrition · 2026Review
- Development of Value-Added Food Products from European Catfish (Foods (Basel, Switzerland) · 2026Article
- Impact of Elexacaftor/Tezacaftor/Ivacaftor on Fat-Soluble Vitamin Status in 2 to 5 Year-Old Children Using a Cystic Fibrosis-Specific Multivitamin Formulation.Children (Basel, Switzerland) · 2026Article
- Dietary Effects of Carotenoid-Biofortified Wheat on Feed Conversion and Tissue Antioxidant Concentrations in Broiler Chickens.Foods (Basel, Switzerland) · 2026Article
- Carnivore Diet: A Scoping Review of the Current Evidence, Potential Benefits and Risks.Nutrients · 2026Article
- Vitamin A Derivatives and Adipose Tissue Differentiation: Molecular Pathways Driving Browning and Anti-Obesity Effects.Current obesity reports · 2026Review
81 more citing papers are in PubMed but not listed here.
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Abstract
Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derived Dietary Reference Values (DRVs) for vitamin E. In this Opinion, the Panel considers vitamin E as α-tocopherol only. The Panel considers that Average Requirements (ARs) and Population Reference Intakes (PRIs) for vitamin E (as α-tocopherol) cannot be derived for adults, infants and children, and therefore defines Adequate Intakes (AIs), based on observed intakes in healthy populations with no apparent α - tocopherol deficiency in the EU. This approach considers the range of average intakes of α-tocopherol and of α-tocopherol equivalents estimated by EFSA from dietary surveys in children and adults in nine countries. The Panel notes the uncertainties in the available food composition and consumption data, the fact that most EU food composition databases contain values for vitamin E as α-tocopherol equivalents, as well as the contribution of average α-tocopherol intakes to average α-tocopherol equivalent intakes in these countries. For adults, an AI for α-tocopherol is set at 13 mg/day for men and 11 mg/day for women. For children aged 1 to < 3 years, an AI for α-tocopherol is set at 6 mg/day for both sexes. For children aged 3 to < 10 years, an AI for α-tocopherol is set at 9 mg/day for both sexes. For children aged 10 to < 18 years, an AI for α-tocopherol is set at 13 mg/day for boys and 11 mg/day for girls. For infants aged 7-11 months, an AI for α-tocopherol of 5 mg/day is derived by extrapolating upwards from the estimated α-tocopherol intake in exclusively breast-fed infants aged 0-6 months and rounding. For pregnant or lactating women, the Panel considers that there is no evidence for an increased dietary α-tocopherol requirement, and the same AI is set as for non-pregnant non-lactating women.
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