Evidence map›Paper›PMID 42109774›Full record

ArticleEFSA journal. European Food Safety Authority2015

Enzootic bovine leukosis.

EFSA Panel on Animal Health and Welfare (AHAW)

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
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  7. Review
  8. Performance of 5 commercial ELISA kits for the detection of antibody to bovine leukemia virus.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2025
    Article
  9. Article
  10. Article
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  12. Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

EFSA Panel on Animal Health and Welfare (AHAW)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enzootic bovine leukosis is a disease of cattle caused by bovine leukemia virus (BLV). The virus causes a persistent, life-long infection in a subset of B cells. Malignant tumours (lymphomas) ultimately develop in 2-5% of infected animals, predominantly in adult cattle older than 3-5 years. Lymphomas invariably lead to death of the animal within months. Before 1960, BLV was endemic in dairy herds in Northern/Eastern Europe and North America. Since then it has spread to all continents. The disease has been successfully controlled and eliminated from many countries in Europe. There is no evidence to suggest that any significant reservoir of BLV exists among other species, nor for any role of BLV in human disease or cancers. BLV exhibits a slow, progressive spread within a herd and it is likely to persist if control measures are not applied. The main modes of transmission are perinatal from cow to calf, via colostrum and milk, and close contact that allows transfer of infected lymphocytes, such as dehorning and injections using non-sterile utensils. Transfer between herds is almost entirely by movement of infected animals. Suitable methods have been developed for diagnosis of BLV infection in specimens of blood, milk and lymphomas. EBL has a negative impact on milk yield and leads to increased premature culling. The welfare consequences of lymphomas vary according to the location and magnitude of organ involvement. Criteria for maintaining country freedom from EBL differ substantially between OIE and EU. Surveillance for freedom should be based on a combination of serological testing of adult animals and identification of lymphomas at slaughter.

Indexed as

Bovine leukemia viruscontrolimpactleukosislymphoma

Identifiers

PMID42109774
PMCPMC13151565

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.