Evidence map›Paper›PMID 42109762›Full record

ReviewDiscover public health2026

Mobile health applications for enhancing mental health access and outcomes among adolescents and young people living with HIV: a systematic review.

Carlos Muleya, Rosemary N Likwa, Jacqueline J Folotiya, Jeremia Banda, Peter J Chipimo, Patricia Sakala, Melvin Salati, Chikoloma Nakazwe, Linah K Mwango, Caitlin Baumhart and 3 more

Abstract readReview
In one paragraph

Review in Discover public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carlos MuleyaUniversity of Zambia, Lusaka, Zambia.ORCID 0000-0001-7255-7287
Rosemary N LikwaUniversity of Zambia, Lusaka, Zambia.
Jacqueline J FolotiyaUniversity of Zambia, Lusaka, Zambia.
Jeremia BandaUniversity of Zambia, Lusaka, Zambia.
Peter J ChipimoWorld Health Organization, Lusaka, Zambia.
Patricia SakalaCAZACHA Business Solutions Limited, Lusaka, Zambia.
Melvin SalatiCAZACHA Business Solutions Limited, Lusaka, Zambia.
Chikoloma NakazweYoung African Statisticians Association, Lusaka, Zambia.
Linah K MwangoCiheb Zambia, Lusaka, Zambia.
Caitlin BaumhartInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD USA.
Cassidy W ClaassenInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD USA.
Naeem DalalZambia National Public Health Institute, Lusaka, Zambia.
Loyd B MulengaMinistry of Health, Lusaka, Zambia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mental health (MH) disorders remain a major global public health concern, disproportionately affecting adolescents and young people living with HIV (AYPLHIV). Limited access to MH services, stigma, and a shortage of trained professionals hinder effective care, particularly in low-resource settings. Mobile health (mHealth) applications have emerged as accessible and scalable tools for improving MH support and reducing disparities in service delivery. This systematic review assessed the effectiveness of mHealth applications in improving access to MH services and outcomes among AYPLHIV and comparable populations globally. Methods: A systematic search was conducted across PubMed, PsycINFO, Web of Science, and the Cochrane Library for studies published between January 2020 and March 2025. Eligible studies evaluated mobile or app-based interventions designed to enhance MH access, engagement, or outcomes. Systematic reviews, meta-analyses, SMS-only interventions, and non-empirical studies were excluded. Two independent reviewers (CM and PS) screened articles, extracted data, and assessed study quality using the Joanna Briggs Institute (JBI) Critical Appraisal Tools. Data were synthesized narratively following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 framework. Results: Of 265 records identified, 16 empirical studies met the inclusion criteria. The studies covered Africa (Ethiopia, Kenya), Asia (Indonesia, Vietnam, Iran, Malaysia), Europe (Spain, Poland, United Kingdom), North America (USA), and Oceania (Australia), and employed randomized controlled trials, mixed-methods, pre-post, and cross-sectional designs. Across studies, mobile interventions consistently improved user engagement, accessibility, and MH outcomes, including significant reductions in depression, anxiety, and stress symptoms ( Conclusions: mHealth applications substantially improve access to and delivery of MH services for AYPLHIV and related groups. Integration of these tools into existing health systems, combined with culturally tailored design, ethical AI use, and sustainability strategies, can strengthen MH care globally. Future research should address long-term impact, cost-effectiveness, and equity in implementation. Supplementary Information: The online version contains supplementary material available at 10.1186/s12982-026-01998-9.

Indexed as

AccessAdolescents and young peopleHIVMental healthMobile applications

Identifiers

PMID42109762
PMCPMC13149599

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.