ArticleFrontiers in oncology2026
The impact of positioning errors on the dose distribution of hypofractionated radiotherapy for left-sided radical breast cancer.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To evaluate the impact of setup errors on the dosimetry of targets and organs at risk (OARs) in the mode of Hypofractionated radiotherapy(HFRT) for left-sided radical breast cancer, particularly on the esophagus, thyroid and left anterior descending artery (LAD). Methods: 30 patients were prescribed with 43.5Gy in 15 fractions. Positioning uncertainties were simulated by shifting the isocenter of 3, 5, 7, and 9 mm in six directions. Deviations in dosimetry were analyzed for the supraclavicular and the chest wall clinical target volume (CTV Results: For D Conclusion: The esophagus and thyroid are most sensitive to setup errors in the right direction, while the heart, LAD, and lung are most sensitive to errors in the posterior direction. It is recommended that the setup error tolerance be set at 3 mm for the CTV
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