Evidence map›Paper›PMID 42109605›Full record

ArticleImmune network2026

Recombinant Japanese Encephalitis Virus Envelope Antigen Presented on CoPoP Liposomes Elicits Cellular Immunity and Protects Mice From Lethal Challenge.

Seung Yong Kim, In Ryeong Jung, Hyojung Park, Jin Ouk Choi, Sang Hyeon Kim, Jimin Pak, Jinil Kim, Cheoljun Choi, Seung Yeon Kwon, Kiho Jeong and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immune network, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Seung Yong KimDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul 03722, Korea.
In Ryeong JungDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul 03722, Korea.
Hyojung ParkDepartment of Pediatrics, Yonsei University College of Medicine, Seoul 03722, Korea.
Jin Ouk ChoiSchool of Biological Sciences, Seoul National University, Seoul 08826, Korea.
Sang Hyeon KimDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul 03722, Korea.
Jimin PakSchool of Biological Sciences, Seoul National University, Seoul 08826, Korea.
Jinil KimEuBiologics, R&D Center, EuBiologics Co., Ltd., Seoul 06778, Korea.
Cheoljun ChoiEuBiologics, R&D Center, EuBiologics Co., Ltd., Seoul 06778, Korea.
Seung Yeon KwonEuBiologics, R&D Center, EuBiologics Co., Ltd., Seoul 06778, Korea.
Kiho JeongEuBiologics, R&D Center, EuBiologics Co., Ltd., Seoul 06778, Korea.
Nari KimEuBiologics, R&D Center, EuBiologics Co., Ltd., Seoul 06778, Korea.
Jiseon KimGraduate School of Medical Science, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul 03722, Korea.
Ki Taek NamGraduate School of Medical Science, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul 03722, Korea.
Dae Gwin JeongBionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Doo Hee ShimDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul 03722, Korea.
Jae Myun LeeDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul 03722, Korea.
Ji-Man KangDepartment of Pediatrics, Yonsei University College of Medicine, Seoul 03722, Korea.
Soo Seok HwangSchool of Biological Sciences, Seoul National University, Seoul 08826, Korea.
June-Yong LeeDepartment of Microbiology and Immunology, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID https://orcid.org/0000-0002-4476-725X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Japanese encephalitis virus (JEV) causes severe encephalitis in endemic regions, and vaccination remains the primary preventive measure. To develop subunit vaccines that enhance cellular immunity, we produced a soluble His-tagged recombinant JEV envelope (rJEV-E) ectodomain and particularized it on cobalt porphyrin-phospholipid (CoPoP) immunogenic liposomes containing an monophosphoryl lipid A-related TLR4 agonist, with or without

Indexed as

Cellular immunityCobalt porphyrin–phospholipid (CoPoP) liposomeJapanese encephalitis virusQS-21Recombinant envelope (E) antigenSubunit vaccine

Identifiers

PMID42109605
PMCPMC13150426

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.