ArticleO&G open2026
Immunoglobulin G4-Related Disease of the Genitourinary System.
Article in O&G open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImmunoglobulin G4-related disease (IgG4-RD) is an immune-mediated disease that is often misdiagnosed given its rare incidence and misleading presentation. Prior case studies have described IgG4-RD involving the ovaries, uterus, and bladder. This article describes the first case of vaginal IgG4-RD. CASE: A 76-year-old woman presented with episodes of vaginal spotting, vaginal cuff friability, and benign inflammation on vaginal pathology. She was unsuccessfully treated with topical estrogen and antibiotics. She ultimately was found to have a progressive, obstructive pelvic mass near the vaginal cuff that was surgically excised, with mass pathology showing lymphoplasmacytic disease. The mass recurred and repeat sampling of the vaginal apex confirmed IgG4-RD.
conclusionThis report showcases the novel finding of vaginal IgG4-RD. The patient's decade-long course before diagnosis highlights the challenges in identifying this disease. This case report aims to increase awareness of vaginal IgG4-RD, leading to timely diagnosis and treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.