Evidence map›Paper›PMID 42109576›Full record

ReviewPlant-environment interactions (Hoboken, N.J.)2026

Genome Editing in Root and Tuber Crop Development in Sub-Saharan Africa.

Himanshu Saini, Rohit Kumar, Manjeet, Srinu Banothu, Suram Likhita Reddy, Rajesh Gudihalli Munivenkatappa, Sri Sai Siddartha Naik, Roop Kumar, Rahul Pradhan

Abstract readReview
In one paragraph

Review in Plant-environment interactions (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Himanshu SainiSchool of Applied Natural Science Adama Science and Technology University Adama Ethiopia.ORCID https://orcid.org/0009-0000-7852-6262
Rohit KumarFaculty of Agricultural Sciences GLA University Mathura Uttar Pradesh India.
ManjeetFaculty of Agricultural Sciences Shree Guru Gobind Singh Tricentenary University Gurugram Haryana India.ORCID https://orcid.org/0000-0002-2694-7409
Srinu BanothuSchool of Agriculture SR University Warangal Telangana India.
Suram Likhita ReddyDepartment of Agronomy Marwadi University Rajkot Gujrat India.
Rajesh Gudihalli MunivenkatappaDepartment of Crop Management Kumaraguru Institute of Agriculture Erode Tamil Nadu India.ORCID https://orcid.org/0009-0004-6130-3635
Sri Sai Siddartha NaikDepartment of Agronomy PJTAU Agricultural College Warangal Telangana India.
Roop KumarSchool of Agriculture Lovely Professional University Phagwara Punjab India.
Rahul PradhanSilviculture and Forest Management Division Institute of Wood Science and Technology (ICFRE-IWST) Bengaluru India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precision genome editing, particularly using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), is advancing crop improvement by enabling targeted and efficient genetic modifications. Root and tuber crops such as potato, cassava, sweet potato, and yam are vital for global food and nutritional security but remain highly vulnerable to climate change, pests, diseases, and limited genetic diversity. Genome editing technologies facilitate the development of improved traits, including enhanced disease resistance, tolerance to abiotic stress, improved nutritional quality, and extended shelf life. This review synthesizes recent advances in genome editing for root and tuber crops across global production systems, including illustrative examples from Sub-Saharan Africa, where active genome editing initiatives are being implemented. It further examines key technical constraints, such as low efficiency of plant transformation and regeneration, and highlights regulatory challenges arising from differing policy frameworks across countries. Emerging solutions are discussed, including genotype-independent editing strategies and DNA-free approaches that avoid the integration of foreign genetic material. Addressing these challenges will be critical for developing resilient and sustainable food systems. Unlike previous reviews, this study integrates mechanistic insights with cross-crop synthesis and proposes next-generation genome editing strategies for engineering complex traits in polyploid root and tuber crops.

Indexed as

climate change resilienceCRISPR/Cas9crop improvementprecision genome editingroot and tuber crops

Identifiers

PMID42109576
PMCPMC13156241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.