ArticleOrthopedic reviews2026
Association Between Femoral Neck Bone Mineral Density and Osteoporotic Fracture Counts in U.S. Adults: A NHANES 2005-2020 Analysis.
Article in Orthopedic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Bone mineral density (BMD) is a key determinant of osteoporotic fracture risk; however, the association between femoral neck BMD and fracture burden across different sex and age groups remains incompletely characterized. Methods: We conducted a cross-sectional analysis using NHANES data from 2005-2010, 2013-2014, and 2017-March 2020. Participants aged ≥50 with femur neck BMD and fracture history were included. Survey-weighted negative binomial regression models and restricted cubic spline analyses were applied to evaluate the association between femoral neck BMD and osteoporotic fracture counts, with stratified analyses by sex and age. Results: In fully adjusted models, higher femoral neck BMD was associated with lower hip and total osteoporotic fracture counts. Restricted cubic spline analyses demonstrated a nonlinear inverse association between femoral neck BMD and predicted fracture counts. Sex- and age-stratified analyses revealed substantial heterogeneity in these associations, with a stronger inverse relationship observed among older adults, with more consistent inverse patterns among females and age-dependent associations among males. Discussion: Femoral neck BMD is inversely associated with osteoporotic fracture burden in U.S. adults aged ≥50 years, with marked variation by sex and age. These findings highlight the importance of considering demographic heterogeneity when assessing fracture risk using BMD measurements.
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