ArticleInternational journal of dentistry2026
Survival Trends Associated With Histopathological Risk Factors in Oral Squamous Cell Carcinoma.
Article in International journal of dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Survival Trends Associated With Histopathological Risk Factors in Oral Squamous Cell Carcinoma.International journal of dentistry · 2026Article
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Authors and funding
5 authors.
Funding
Abstract
Background: Histopathological risk assessment models in oral squamous cell carcinoma (OSCC) have had varying degrees of success in stratifying patients, with models developed on retrospective cohorts being able to predict recurrence and metastasis. In spite of mounting evidence on their impact on survival outcomes, the incorporation of histopathological features, including perineural invasion (PNI) and the worst pattern of invasion, in staging and risk stratification is still lacking. Thus, our study aimed to assess and characterise histological prognostic indicators in OSCC, elucidate their significance in relation to patient prognosis, and develop a risk assessment model by correlating these indicators with survival parameters and risk stratification. Methods: A retrospective chart audit was performed, and histologic parameters were staged according to the American Joint Committee on Cancer's 8th Edition Cancer Staging Manual and objectively scored based on the College of American Pathologists' (CAP) Protocol 2018. Pearson's chi-square test and Kaplan-Meier survival analysis were carried out to identify the significant correlations between specific histopathological indicators and patient prognosis. Results: Higher grades of pattern of invasion were significantly associated with greater PNI and depth of invasion ( Conclusion: The development of a risk stratification model based on these indicators provides a valuable tool for enhancing patient outcomes. Incorporation of detailed histopathological analysis into routine clinical decision-making improves survival rates and treatment efficacy in OSCC patients.
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