Evidence map›Paper›PMID 42109477›Full record

ArticleFrontiers in pediatrics2026

Assessment of treatment effectiveness, follow-up results, and recurrence patterns in children with

Mengde Luo, Danli Wei, Ling Jin, Yiling Wei

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Mengde Luo *Department of Pediatrics, Liuzhou People's Hospital, Liuzhou, China.
Danli Wei *Department of Pediatrics, Liuzhou People's Hospital, Liuzhou, China.
Ling JinDepartment of Pediatrics, Liuzhou People's Hospital, Liuzhou, China.
Yiling WeiDepartment of Pediatrics, Liuzhou People's Hospital, Liuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Materials and methods: This retrospective observational study was conducted at the Department of Pediatrics, Liuzhou People's Hospital, between January 2023 and December 2025. Children aged 4-13 years with confirmed Results: A total of 128 children were included in the analysis. The overall eradication rate was 79.7%. The amoxicillin-based regimen demonstrated higher efficacy (84.0%) compared with the metronidazole-based regimen (67.6%). Recurrence occurred in 13.7% of successfully treated patients, predominantly among children younger than 10 years. Most recurrence cases were identified between 6 and 12 months following confirmed eradication. Conclusion: Amoxicillin-based triple therapy achieved superior eradication rates compared to metronidazole-based therapy in this children's cohort. However, recurrence remains a clinically relevant concern, particularly in younger children. Structured long-term follow-up and region-specific antimicrobial resistance surveillance are essential to optimize treatment outcomes in children's

Indexed as

amoxicillinclarithromycinHelicobacter pylorimetronidazolepediatric gastroenterology

Identifiers

PMID42109477
PMCPMC13149433

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.