Evidence map›Paper›PMID 42109423›Full record

ArticleBioinformation2026

Comparative assessment of injectable platelet-rich fibrin versus concentrated growth factor for periodontal intrabony defects.

Yasir S Khan, Rishiraj Singh Karki, Tanu Sahney, Shahrukh Khan, Varanasi Haripriya, Pritam Bora

Abstract read
In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yasir S KhanDepartment of Periodontology, Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Lucknow, Uttar Pradesh, India.
Rishiraj Singh KarkiDepartment of Dentistry, Government Doon Medical College and Hospital, Dehradun, India.
Tanu SahneyDepartment of Periodontology, Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Lucknow, Uttar Pradesh, India.
Shahrukh KhanDepartment of Periodontology, Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Lucknow, Uttar Pradesh, India.
Varanasi HaripriyaClinical Practioner, Sri Visweswara Dental Care and Implant Centre, Vishakhapatnam, Andhra Pradesh, India.
Pritam BoraDepartment of Periodontology, Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Lucknow, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal intrabony defects present a therapeutic challenge and direct clinical evidence comparing injectable platelet-rich fibrin (i-PRF) and concentrated growth factor (CGF) as regenerative materials remains limited. This randomized controlled split-mouth clinical trial included 20 patients with 40 comparable three-wall intrabony defects treated by open flap debridement followed by either i-PRF or CGF, with clinical and radiographic parameters evaluated at baseline and 6 months. Both groups showed significant improvements in probing pocket depth, clinical attachment level and radiographic defect fill at 6 months (p<0.001). The CGF group demonstrated significantly greater pocket depth reduction, attachment gain and percentage of radiographic defect fill compared with the i-PRF group (p<0.05). Within the limitations of this study, both materials were effective, although CGF exhibited superior regenerative outcomes and may represent a more predictable option for periodontal intrabony defect regeneration.

Indexed as

concentrated growth factor (CGF)injectable platelet-rich fibrin (i-PRF)intrabony defectsperiodontal regenerationPeriodontitisrandomized controlled trial

Identifiers

PMID42109423
PMCPMC13150195

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.