Evidence map›Paper›PMID 42109420›Full record

ArticleBioinformation2026

Bispectral index-guided versus standard anaesthesia monitoring for intraoperative awareness prevention.

Brajesh Kumar, Nancy Ekka, Aditya Singh Chauhan, Sourabh Shrivastava

Abstract read
In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brajesh KumarConsultant Anaesthesiologist, Bansal Hospital, Sagar, Madhya Pradesh, India.
Nancy EkkaDepartment of Anaesthesiology, Gajra Raja Medical college Gwalior, Madhya Pradesh, India.
Aditya Singh ChauhanDepartment of Anaesthesiology, Gajra Raja Medical college Gwalior, Madhya Pradesh, India.
Sourabh ShrivastavaDepartment of Anaesthesiology, Gajra Raja Medical college Gwalior, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although bispectral index (BIS) monitoring provides an objective measure of hypnotic depth, its routine use to prevent awareness remains debated due to conflicting evidence and cost considerations. Therefore, it is of interest to evaluate BIS-guided versus clinically guided sevoflurane anaesthesia in 200 adults undergoing elective surgery over 60 minutes. No definite intraoperative awareness occurred in either group, confirmed by modified Brice interviews up to 30 days postoperatively. BIS monitoring reduced sevoflurane consumption by 24% (1.7 ± 0.4 vs 2.2 ± 0.5 MAC-hours; p < 0.001) and accelerated extubation (7.9 ± 2.3 vs 10.8 ± 3.1 min; p < 0.001) and PACU discharge (46.2 ± 11.8 vs 56.9 ± 14.7 min; p < 0.001). It also provided greater haemodynamic stability, with lower MAP variability (11.4 ± 3.9% vs 16.8 ± 5.6%; p < 0.001). BIS monitoring optimizes anaesthetic delivery and recovery efficiency without lowering awareness incidence compared to vigilant clinical monitoring.

Indexed as

Bispectral index (BIS)depth of anaesthesia monitoringexplicit recallhaemodynamic stabilityintraoperative awarenessrecovery profilesevoflurane consumption

Identifiers

PMID42109420
PMCPMC13150227

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.