Evidence map›Paper›PMID 42109404›Full record

ArticleBioinformation2026

Global longitudinal strain for early detection of subclinical left ventricular systolic dysfunction in patients with systemic lupus erythematosus at a tertiary care centre: A hospital-based study.

Krati Mishra, Vinod Khandait, Kaustubh Telang, Suresh Sarwale, Dheeraj Karde, Saransh Barai

Abstract read
In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Krati MishraDepartment of Medicine, Government Medical College & Hospital (GMCH), Nagpur, India.
Vinod KhandaitDepartment of Medicine, Government Medical College & Hospital (GMCH), Nagpur, India.
Kaustubh TelangDepartment of Rheumatology, SSH Nagpur, India.
Suresh SarwaleDepartment of Cardiology, Super Speciality Hospital (SSH), Nagpur, India.
Dheeraj KardeDepartment of Cardiology, Super Speciality Hospital (SSH), Nagpur, India.
Saransh BaraiDepartment of Medicine, Government Medical College & Hospital (GMCH), Nagpur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic Lupus Erythematosus (SLE) silently affects cardiac function, requiring early myocardial dysfunction detection to prevent morbidity. This hospital-based cross-sectional study assessed 49 SLE patients (2019 ACR/EULAR criteria) via clinical exam, Electrocardiogram (ECG) and echocardiography including speckle-tracking Global Longitudinal Strain (GLS). Evaluated parameters included Left Ventricular Ejection Fraction (LVEF), diastolic function, valvular lesions, pericardial effusion, pulmonary pressures and GLS (values < -16% indicating subclinical systolic dysfunction). Abnormal GLS occurred in 55.1%, with 28.5% showing preserved LVEF but impaired GLS, alongside systolic dysfunction (63.2%) and diastolic dysfunction (14.2%). GLS advances SLE cardiac screening by detecting subclinical LV impairment before LVEF decline, enabling timely intervention in preserved ejection fraction patients.

Indexed as

echocardiographyglobal longitudinal strain (GLS)left ventricular functionspeckle trackingsubclinical systolic dysfunctionSystemic lupus erythematosus (SLE)

Identifiers

PMID42109404
PMCPMC13150178

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.