Evidence map›Paper›PMID 42109391›Full record

ArticleBioinformation2026

Oral health considerations in patients receiving antidepressant therapy: Clinical implications and management strategies.

Pihu Jamwal, P K Monika, Aditi Pustake, Nisha Dholakiya, Roshani Shrestha, Ketki Joshi

Abstract read
In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pihu JamwalDepartment of Dentistry, Institute of Dental Sciences, Jammu & Kashmir, India.
P K MonikaDepartment of Prosthodontics, Lenora Institute of Dental Sciences, Rajahmundry, Andhra Pradesh, India.
Aditi PustakeDepartment of Dentistry, Sharad Pawar Dental College and Hospital, Sawangi (Meghe), Wardha, Maharashtra, India.
Nisha DholakiyaDepartment of Dentistry, College of Dental Science and Research Center, Gujarat, India.
Roshani ShresthaDepartment of Dentistry, Nepal Medical College and Teaching Hospital, Gokarneshwar, Kathmandu, Nepal.
Ketki JoshiDepartment of Dentistry, Tatyasaheb Kore Dental College and Research Center, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients receiving antidepressant therapy frequently present with oral health complications that are under recognized and inadequately addressed in routine dental practice. Antidepressant medications-particularly selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs)-are widely prescribed and have significant implications for oral health. Their adverse effects include xerostomia, increased caries risk, periodontal disease and bruxism and delayed wound healing, while depression itself may contribute to poor oral hygiene practices and irregular dental attendance. Additionally, pharmacologic interactions with vasoconstrictors, analgesics, antibiotics and antifungals can complicate dental management, particularly in medically compromised and geriatric patients. This review integrates pharmacologic, behavioral and clinical considerations related to antidepressant use and translates existing evidence into practical strategies for comprehensive dental management, thereby providing a clinically relevant framework for dental practitioners.

Indexed as

Antidepressantsdental cariesoral health managementperiodontal diseasexerostomia

Identifiers

PMID42109391
PMCPMC13150264

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.