Evidence map›Paper›PMID 42109339›Full record

ArticleBioinformation2026

Diagnostic performance of serum CA-125 and ultrasonography in ovarian tumour differentiation.

Halima Khanam, Mehriban Amatullah, Rebeka Sultana M S T, Saraban Tohura, Farzana Sharmin, Naznin Akter Zahan, Irin Haque, Romena Afroj

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In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Halima KhanamDepartment of Gynaecological Oncology, Bangladesh Medical University, Dhaka, Bangladesh.
Mehriban AmatullahDepartment of Obstetrics and Gynecology, Bangladesh Medical University, Dhaka, Bangladesh.
Rebeka Sultana M S TDepartment of Gynaecological Oncology, Bangladesh Medical University, Dhaka, Bangladesh.
Saraban TohuraDepartment of Obstetrics and Gynecology, Aalok Mother and Childcare Hospital, Dhaka, Bangladesh.
Farzana SharminDepartment of Obstetrics and Gynecology, Bangladesh Medical University, Dhaka, Bangladesh.
Naznin Akter ZahanGynaecological Oncology, Directorate General of Health Services (DGHS), Dhaka, Bangladesh.
Irin HaqueDepartment of Obstetrics and Gynecology, Directorate General of Health Services (DGHS), Dhaka, Bangladesh.
Romena AfrojDepartment of Obstetrics and Gynecology, Bangladesh Medical University, Dhaka, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early differentiation of benign versus malignant ovarian tumours is crucial for optimal management but remains challenging in many clinical settings. This analytical cross-sectional study at Rangpur Medical College Hospital, Bangladesh, included 62 surgically managed ovarian tumours (48 benign, 14 malignant) evaluated preoperatively by transabdominal ultrasonography and serum CA-125. Ultrasonography alone yielded a sensitivity of 57.42%, specificity 89.50%, PPV 61.84%, NPV 87.42% and accuracy 82.17%. Serum CA-125 showed better performance, with a sensitivity 71.42%, specificity 93.75%, PPV 76.92%, NPV 91.83% and accuracy 88.70%. Combining ultrasonography with CA-125 improved diagnostic accuracy to 91.32% (sensitivity 78.57%, specificity 93.75%), advancing preoperative triage by providing a simple, high-yield strategy for resource-limited settings.

Indexed as

CA-125diagnostic accuracyOvarian tumourultrasonography

Identifiers

PMID42109339
PMCPMC13150239

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