Evidence map›Paper›PMID 42109197›Full record

ArticleEuropean journal of pain (London, England)2026

Prognostic Factors of High Healthcare Utilization Costs Among People With Spinal Disorders Using a Spine Registry Linked to Public Healthcare Data.

Daniel Feller, Bjørnar Berg, Ørjan Nesse Vigdal, Lise Grethe Kjønø, Maja Wilhelmsen, Bart Koes, Margreth Grotle, Alessandro Chiarotto

Abstract read
In one paragraph

Article in European journal of pain (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel FellerDepartment of General Practice, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0001-9853-3486
Bjørnar BergCentre for Intelligent Musculoskeletal Health, Faculty of Health Science, OsloMet-Oslo Metropolitan University, Oslo, Norway.
Ørjan Nesse VigdalCentre for Intelligent Musculoskeletal Health, Faculty of Health Science, OsloMet-Oslo Metropolitan University, Oslo, Norway.
Lise Grethe KjønøCentre for Intelligent Musculoskeletal Health, Faculty of Health Science, OsloMet-Oslo Metropolitan University, Oslo, Norway.
Maja WilhelmsenNorwegian Neck and Back Registry, University Hospital of North Norway, Tromsø, Norway.
Bart KoesDepartment of General Practice, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Margreth GrotleAzienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy.
Alessandro ChiarottoDepartment of General Practice, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpinal disorders are associated with substantial healthcare costs, but prognostic factors associated with high spine-related healthcare expenditures remain insufficiently understood. Therefore, this study aimed to identify prognostic factors associated with spine-related healthcare costs among patients with spinal disorders.

methodsA prognostic factor study using data from the Norwegian Neck and Back Registry was conducted. Thirty-four potential prognostic factors were considered. Spine-related healthcare costs were analyzed as a continuous outcome. Continuous predictors were modelled using restricted cubic splines to account for potential non-linear associations. Univariable and multivariable adjusted models were fitted, with priori defined covariate adjustments.

resultsThe study included 7877 patients with spinal pain. In adjusted models, healthcare region (patients from the Mid-Norway, West and Southeast regions incurred 69.1%, 44.5% and 29.6% higher costs, respectively, compared with those in the North), disability (90th vs. 10th percentile: +29.2%; CI +11.9% to +49.2%), pain during activity (90th vs. 10th percentile: +23.4%; CI +7.6% to +41.6%), health-related quality of life (90th vs. 10th percentile: -21.3%; CI -31.1% to -10.0%), job satisfaction (90th vs. 10th percentile: +14.7%; CI +2.3% to +28.7%), and opioid use (+15.3%; CI +5.7% to +26.2%) were associated with healthcare costs.

conclusionsThis set of identified prognostic factors may be useful for characterizing patient subgroups, developing prognostic models to identify individuals at risk of high healthcare expenditures, and informing strategies to improve the efficiency and equity of healthcare resource allocation. SIGNIFICANCE: This study identifies clinical and societal determinants of health associated with high spine-related healthcare costs, highlighting how these factors jointly drive resource use. These findings help clarify mechanisms underlying cost variation and support the future development of prognostic tools and targeted strategies to improve efficiency and equity in spine care.

Indexed as

Health Care CostsPatient Acceptance of Health CareSpinal DiseasesAdultAgedFemaleHumansMaleMiddle AgedNorwayPrognosisQuality of LifeRegistrieshealthcare costsprognosisprognostic factorsspinal disorders

Identifiers

PMID42109197
PMCPMC13158898

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.