ArticleMagnetic resonance in medicine2026
Combining Oxygen-Enhanced MRI and Electron Paramagnetic Resonance Oximetry for Quantitative OE-MRI (qOE-MRI) as a Method for Mapping Absolute Oxygen Levels (pO
Conner S Ubert, Victor B Kassey, Maciej M Kmiec, Diana J Wallin, Alireza Kheirollah, Sergey V Petryakov, Ryan C O'Connell, Philip E Schaner, Periannan Kuppusamy
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In one paragraphArticle in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
9 authors.
Victor B KasseyDepartment of Radiology, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Maciej M KmiecDepartment of Radiology, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Diana J WallinDepartment of Psychiatry, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Alireza KheirollahDepartment of Surgery, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Sergey V PetryakovDepartment of Radiology, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Ryan C O'ConnellDepartment of Radiology, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Philip E SchanerDepartment of Radiation Oncology and Applied Sciences, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Funding
Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Daniel G. Stover · 1985 to 2026
$132.3MTranslational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3MUltrastructural analysis of axonal Kv2-mediated endoplasmic reticulum/plasma membrane (ER/PM) junctionsP20GM103506 · NIGMS · DARTMOUTH COLLEGE · PI STEVEN FIERING · 2012 to 2026
$60.1MProbes and Methods for Clinical OximetryR01EB004031 · NIBIB · OHIO STATE UNIVERSITY · PI KUPPUSAMY, PERIANNAN · 2004 to 2021
$7.1MMultimodal Marker for imaging oximetry in radiotherapyR01CA269234 · NCI · DARTMOUTH COLLEGE · PI PERIANNAN KUPPUSAMY · 2023 to 2026
$3.0MNovel oxygen monitoring system for on-site use in the clinicR01EB036124 · NIBIB · DARTMOUTH COLLEGE · PI PERIANNAN KUPPUSAMY · 2024 to 2026
$949kDartmouth Cancer Center "Big-bet" P30CA023108Geisel School of Medicine at Dartmouth DCC Irradiation, Imaging, Microscopy and Animal Cancer Models Core Facility NH-INBRE P20GM103506Geisel School of Medicine at Dartmouth DCC Irradiation, Imaging, Microscopy and Animal Cancer Models Core Facility RRID:SCR_025077NCI NIH HHS P30 CA016058NCI NIH HHS P30 CA023108NCI NIH HHS R01 CA269234NIBIB NIH HHS R01 EB004031NIBIB NIH HHS R01 EB036124NIGMS NIH HHS P20 GM103506NIH HHS R01 CA269234NIH HHS R01 EB 004031NIH HHS R01 EB036124
6 · The paper itselfAbstract
purposeTumor hypoxia remains a major barrier to effective radiation therapy, yet no current imaging technique can generate spatially resolved, absolute pO
methodsPhantom studies at 9.4 T validated the linearity of the R
resultsPhantom validation demonstrated excellent R
conclusionqOE-MRI enables repeatable and spatially resolved absolute tumor pO
Indexed as
Magnetic Resonance ImagingOximetryOxygenAnimalsCell Line, TumorElectron Spin Resonance SpectroscopyGoldMicePhantoms, ImagingTumor HypoxiaGoldOxygenEPR oximetryOE‐MRIOxyChipSCC7 tumortumor hypoxia
Identifiers
PMID42108753
PMCPMC13270811
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