Evidence map›Paper›PMID 42108737›Full record

ArticleJournal of microbiology and biotechnology2026

Optimization of Culture Conditions for Pyrroloquinoline Quinone-Overproducing Mutant

Jiwon Lee, Hyunjoo Hwang, Gamin Kim, Peter Hinterdorfer, Soyoun Song, Kisung Ko

Abstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiwon LeeBioSystems Design Lab, Department of Medicine, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Hyunjoo HwangBioSystems Design Lab, Department of Medicine, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Gamin KimBioSystems Design Lab, Department of Medicine, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Peter HinterdorferDepartment of Applied Experimental Biophysics, Institute of Biophysics, Johannes Kepler University Linz 4040 Linz, Austria.
Soyoun SongNovepharma Inc., Yongin 17095, Republic of Korea.
Kisung KoBioSystems Design Lab, Department of Medicine, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyrroloquinoline quinone (PQQ) is a water-soluble quinone derived from bacteria, known for its antioxidant properties and ability to enhance mitochondrial function. These characteristics make PQQ a promising bioactive molecule for anti-aging applications in dermatology. This study aimed to improve PQQ production by developing a UV-induced mutant strain and optimizing the culture medium, and to evaluate the potential of the produced PQQ as a cosmetic ingredient. The mutant strain, NPP-230, was compared with the wild-type strain,

Indexed as

PQQ CofactorSkinAntioxidantsCollagenCulture MediaMelaninsMonophenol MonooxygenaseMutationAntioxidantsCollagenCulture MediaMelaninsMonophenol MonooxygenasePQQ CofactorMutant strainOptimized culture conditionsPyrroloquinoline quinone (PQQ)Skin physiology

Identifiers

PMID42108737
PMCPMC13158751

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.