ArticleJournal of gynecologic oncology2026
Recent patterns and trends in global ovarian cancer incidence and mortality in adolescents and young adults.
Article in Journal of gynecologic oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveOvarian cancer in adolescents and young adults (AYAs, aged 15-39 years) presents distinct clinical and epidemiological characteristics, yet comprehensive global epidemiological data remain limited.
methodsWe conducted a comprehensive analysis using 3 International Agency for Research on Cancer databases: GLOBOCAN 2022, Cancer Incidence in Five Continents Plus, and World Health Organization (WHO) mortality database. Age-standardized incidence rates (ASIRs) and mortality rates (ASMRs) per 100,000 women-years were calculated using the WHO World Standard Population. Countries were stratified by Human Development Index (HDI). Temporal trends were analyzed using Joinpoint regression to calculate annual percent change and average annual percent change (AAPC).
resultsIn 2022, global ASIRs for AYAs (15-39 years) ovarian cancer demonstrated relative uniformity across regions, with highest rates in Melanesia. ASMRs exhibited an inverse HDI gradient, with low-HDI regions experiencing highest mortality burdens (0.75 per 100,000 women-years) despite lower incidence (2.02 per 100,000 women-years). Analysis of the most recent 5-year period revealed divergent trends, characterized by a significant rise in incidence in Thailand (AAPC=6.62%; 95% confidence interval [CI]=1.84%, 11.52%) across 44 regions and marked mortality elevations in the Syrian Arab Republic (AAPC=15.89%; 95% CI=10.29%, 21.64%) and Venezuela (AAPC=11.08%; 95% CI=8.06%, 14.01%) in 59 regions.
conclusionDespite relatively uniform global incidence, mortality from ovarian cancer in AYAs shows pronounced international disparities, with the greatest burden concentrated in low-HDI regions. Evidence from divergent incidence-mortality trajectories indicating that healthcare improvements enhance survival highlights the critical need for targeted interventions to address global disparities in AYA ovarian cancer outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.