Evidence map›Paper›PMID 42108654›Full record

ArticleDrug delivery2026

Exploiting the dynamics of hyperthermia-enhanced delivery of thermosensitive liposomal doxorubicin to solid tumors.

Pouya Namakshenas, Johannes Crezee, H Petra Kok

Abstract read
In one paragraph

Article in Drug delivery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pouya NamakshenasDepartment of Radiation Oncology, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
Johannes CrezeeDepartment of Radiation Oncology, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
H Petra KokDepartment of Radiation Oncology, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thermosensitive liposomal (TSL) drug delivery with intravascular release under hyperthermia is a promising approach for chemotherapy of solid tumors, where the hyperthermia schedule strongly influences delivery efficacy. This study uses mathematical modeling to evaluate these effects. A compartmental modeling approach was used to simulate TSL-encapsulated doxorubicin (DOX) delivery. The model was calibrated and validated against published

Indexed as

Antibiotics, AntineoplasticDoxorubicinHyperthermiaHyperthermia, InducedNeoplasmsAnimalsBreast NeoplasmsCell Line, TumorDrug Delivery SystemsDrug Resistance, NeoplasmFemaleHumansLiposomesLung NeoplasmsMicePolyethylene GlycolsAntibiotics, AntineoplasticDoxorubicinliposomal doxorubicinLiposomesPolyethylene Glycolscomputational modelingdrug deliveryhyperthermiaintravascular drug releaseThermosensitive liposomes (TSLs)

Identifiers

PMID42108654
PMCPMC13162552

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.