Evidence map›Paper›PMID 42108585›Full record

ArticleJournal of the American Chemical Society2026

TagC-RED: An Infrared-Triggered Retro-Ene Reaction for Deep-Tissue Bioconjugation.

Sang Mi Suh, Benjamin Ben-Zvi, John M Talbott, Niket Manoj, Brock M Nelson, Riley R Hughes, Graham C Haug, Shohei Koide, Robert S Paton, Monika Raj and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sang Mi SuhDepartment of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.
Benjamin Ben-ZviDepartment of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.
John M TalbottDepartment of Chemistry, Emory University, 1515 Dickey Dr, Atlanta, Georgia 30322, United States.ORCID 0000-0002-1579-1285
Niket ManojDepartment of Chemistry, Colorado State University, 1301 Center Avenue, Ft. Collins, Colorado 80523-1872, United States.
Brock M NelsonDepartment of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.
Riley R HughesDepartment of Chemistry, Emory University, 1515 Dickey Dr, Atlanta, Georgia 30322, United States.ORCID 0000-0002-5924-7775
Graham C HaugDepartment of Chemistry, Colorado State University, 1301 Center Avenue, Ft. Collins, Colorado 80523-1872, United States.
Shohei KoideDepartment of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, and Perlmutter Cancer Center, New York University Langone Health, 522 first Ave, Smilow Research Center, New York, New York 10016, United States.ORCID 0000-0001-5473-4358
Robert S PatonDepartment of Chemistry, Colorado State University, 1301 Center Avenue, Ft. Collins, Colorado 80523-1872, United States.ORCID 0000-0002-0104-4166
Monika RajDepartment of Chemistry, Emory University, 1515 Dickey Dr, Atlanta, Georgia 30322, United States.ORCID 0000-0001-9636-2222
Tianning DiaoDepartment of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.ORCID 0000-0003-3916-8372

Funding

Stereoselective Alkene Carbofunctionalization: Method Development and MechanismR01GM127778 · NIGMS · NEW YORK UNIVERSITY · PI Tianning Diao · 2019 to 2026
$3.1M
NIGMS NIH HHS R01 GM127778
6 · The paper itself

Abstract

Bioconjugation reactions are indispensable for probing biomolecules in their native environments. Photoactivatable bioconjugation offers spatiotemporal control; however, current methods face significant limitations, including the requirement for noncanonical functional groups, cytotoxic heavy-metal catalysts, and high-energy UV or visible light (λ < 800 nm), which restrict tissue penetration and increase phototoxicity risks. In response, we introduce TagC-RED, a

Indexed as

Diazonium CompoundsInfrared RaysAnimalsCysteineMolecular StructureCysteineDiazonium Compounds

Identifiers

PMID42108585
PMCPMC13195677

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.