Evidence map›Paper›PMID 42108559›Full record

ArticleAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2026

Clinical Features, CT Imaging Decisions and Yield by Age in Adults With Abdominal Pain in the Emergency Department.

Ari B Friedman, Michael N Adjei-Poku, Liliana A Schadt, Yang Li, Anne R Cappola, Rachel R Kelz, Ula Hwang, Gopal Kowdley, Aubrey Mwinyogle, N Seth Trueger

Abstract read
In one paragraph

Article in Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Clinical Features, CT Imaging Decisions and Yield by Age in Adults With Abdominal Pain in the Emergency Department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ari B FriedmanDepartment of Emergency Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Michael N Adjei-PokuDepartment of Emergency Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0009-0002-2464-652X
Liliana A SchadtSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yang LiDepartment of Emergency Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Anne R CappolaDivision of Endocrinology, Diabetes, and Metabolism, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Rachel R KelzLeonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ula HwangDepartment of Emergency Medicine, NYU Grossman School of Medicine, New York City, New York, USA.
Gopal KowdleyTidal Health General Surgery, Tidal Health, Salisbury, Maryland, USA.
Aubrey MwinyogleVascular Surgery, Faith Regional Health Services, Norfolk, Nebraska, USA.
N Seth TruegerDepartment of Emergency Medicine Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-8797-2192

Funding

Midcareer Investigator Award in Patient-Oriented Research in AgingK24AG042765 · NIA · UNIVERSITY OF PENNSYLVANIA · PI CAPPOLA, ANNE R · 2013 to 2024
$1.7M
Abdominal Pain in Older Patients in Emergency DepartmentsK23AG080061 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Ari B Friedman · 2023 to 2026
$780k
NIA NIH HHS K23 AG080061NIA NIH HHS K24 AG042765
6 · The paper itself

Abstract

objectivesOlder adults with abdominal pain present diagnostic uncertainty due to less informative histories/exams, broader etiologies, and higher morbidity. Whether ED imaging decisions are calibrated to this risk is unclear. The objective of this study was to compare age-stratified clinical features, CT utilization, and CT diagnostic yield, and to assess how history/physical and clinician pretest suspicion relate to adverse outcomes.

methodsThis was a retrospective cohort analysis of data from a prospective cohort collected from March 2016-January 2017 at a single community teaching hospital emergency department in southwest Baltimore. We analyzed 1169 visits of adults presenting with nontraumatic abdominal pain including 229 (19.6%) aged ≥ 60 years. Patients < 18 years were excluded. Age groups were 18-39, 40-59, ≥ 60 years. Outcomes were CT ordering, acute actionable CT findings, admission, surgery, and a composite of adverse outcomes (any actionable CT finding, admission, surgery, or Emergency General Surgical diagnosis). History and physical examination operating characteristics (e.g., sensitivity/specificity of tenderness, rebound) were also calculated.

resultsOf 1169 visits, 19.6% were aged ≥ 60 years. CT ordering increased with age (41.7%, 66.2%, 70.7% for 18-39, 40-59, ≥ 60; p < 0.001), as did CT yield (18.4%, 31.2%, 37.7%; p < 0.001). Admissions (12.1%, 28.0%, 37.6%) and surgeries (4.6%, 9.0%, 10.6%) also rose with age. Clinician pretest suspicion was similar across age groups. Abdominal tenderness was less sensitive for adverse outcomes in older adults (sensitivity 0.58 in ≥ 60 vs. 0.73 in 18-39 and 0.73 in 40-59), while rebound tenderness was highly specific across ages (specificity 0.98, 0.96, 0.98). The number of potential diagnoses to consider rose with age.

conclusionIn this cohort, CT use and positivity increased with age and key exam findings (e.g., tenderness) being less informative in older adults, despite similar reported clinician pretest suspicion. These results support age-aware imaging decisions and motivate reframing ED abdominal pain as a geriatric-specific chief complaint.

Indexed as

Abdominal PainEmergency Service, HospitalTomography, X-Ray ComputedAdolescentAdultAgedAge FactorsBaltimoreEmergency Room VisitsFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityYoung Adult

Identifiers

PMID42108559
PMCPMC13158444

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.