Evidence map›Paper›PMID 42108396›Full record

ArticleMagnetic resonance in medicine2026

Evaluating the Influence of Injury-Induced Microstructural Variations on the Efficacy of a Diffusion MRI-Derived Axon Diameter Surrogate.

Hannah E Alderson, Chaoqi Mu, Li Min Chen, Mark D Does, Kevin D Harkins

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hannah E AldersonVanderbilt University, Department of Biomedical Engineering, Nashville, Tennessee, USA.ORCID https://orcid.org/0009-0009-0408-4831
Chaoqi MuVanderbilt University, Department of Biomedical Engineering, Nashville, Tennessee, USA.
Li Min ChenVanderbilt University, Department of Biomedical Engineering, Nashville, Tennessee, USA.
Mark D DoesVanderbilt University, Department of Biomedical Engineering, Nashville, Tennessee, USA.
Kevin D HarkinsVanderbilt University, Department of Biomedical Engineering, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0003-3579-9273

Funding

Uncovering the time dependent diffusion coefficient in neural tissue with MRIR01EB031954 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARKINS, KEVIN D · 2021 to 2024
$1.5M
NIH HHS R01EB031954
6 · The paper itself

Abstract

purposeTo investigate the utility of a recently demonstrated diffusion MRI derived axon diameter surrogate measure (∆D

methodsContusion injuries were performed on the thoracic-lumbar spinal cord of adult male rats. Eight weeks post-injury, rats were sacrificed and their spinal cords imaged by MRI and then scanning electron microscopy (SEM). Relationships between the difference in radial diffusivity with diffusion time (∆D

results∆D

conclusionIn the context of contusion injured rat spinal cords, ∆D

Indexed as

AxonsDiffusion Magnetic Resonance ImagingSpinal Cord InjuriesAnimalsDisease Models, AnimalImage Processing, Computer-AssistedMaleMicroscopy, Electron, ScanningRatsRats, Sprague-DawleySpinal Cordaxon diameterdiffusionspinal cord injury

Identifiers

PMID42108396
PMCPMC13327435

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.