ArticleBritish journal of clinical pharmacology2026
Practical dose ranges supporting target vancomycin exposure with AUC-guided dosing in overweight and obese patients: A multicentre retrospective study.
Article in British journal of clinical pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Practical dose ranges supporting target vancomycin exposure with AUC-guided dosing in overweight and obese patients: A multicentre retrospective study.British journal of clinical pharmacology · 2026Article
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13 authors.
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Abstract
aimEvidence supporting area under the concentration-time curve (AUC)-guided vancomycin dosing in overweight and obese patients remains limited. This multicentre retrospective study aimed to identify pragmatic loading dose (LD) and maintenance dose (MD) ranges associated with target AUC attainment in this population.
methodsPatients aged ≥15 years with a body mass index (BMI) ≥ 25 kg/m
resultsAmong 209 patients (median BMI 27.2 kg/m
conclusionIn this multicentre real-world cohort of overweight/obese adults, an LD around 20 mg/kg (ceiling 2 g) was associated with early AUC
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