Evidence map›Paper›PMID 42107926›Full record

ReviewAnais brasileiros de dermatologia

How to minimize pain with local anesthesia and improve patient experiences: a review.

Umer Nadir, Isadora Rinaldo Scaburi, Felipe Bochnia Cerci, George Michael Jeha, Stanislav Nickolaevich Tolkachjov

Abstract readReview
In one paragraph

Review in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Umer NadirEpiphany Dermatology, Dallas, TX, United States; Department of Dermatology, Texas A&M School of Medicine, Dallas, TX, United States; Division of Dermatology, Baylor University Medical Center, Dallas, TX, United States.
Isadora Rinaldo ScaburiDivision of Dermatology, Hospital Universitário Evangélico Mackenzie, Curitiba, PR, Brazil.
Felipe Bochnia CerciDivision of Dermatology, Hospital Universitário Evangélico Mackenzie, Curitiba, PR, Brazil; Clínica Cepelle, Curitiba, PR, Brazil.
George Michael JehaEpiphany Dermatology, Dallas, TX, United States; Division of Dermatology, Baylor University Medical Center, Dallas, TX, United States.
Stanislav Nickolaevich TolkachjovEpiphany Dermatology, Dallas, TX, United States; Department of Dermatology, Texas A&M School of Medicine, Dallas, TX, United States; Division of Dermatology, Baylor University Medical Center, Dallas, TX, United States; Department of Dermatology, University of Texas at Southwestern, Dallas, TX, United States. Electronic address: Stan.tolkachjov@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLocal anesthesia is essential in common procedures in dermatology, but injection and infiltration of anesthetic often cause significant pain, reducing patient comfort and satisfaction.

objectiveTo review evidence-based techniques to reduce pain associated with local anesthetic injection and infiltration. METHODS AND MATERIALS: A narrative review of the literature was performed, and techniques were summarized for clinicians to reference.

resultsTechnical methods to reduce pain include using smaller-gauge needles (30-33G), smaller syringes (1‒3 mL), buffering lidocaine with sodium bicarbonate, inserting the needle at 90 degrees, slow infusion, subcutaneous delivery, and pore-guided injection. Adjuncts such as warming anesthetic, vibration, ice, music, and verbal distraction ("talkesthesia") also reduce patient perception of pain. STUDY LIMITATIONS: Limitations include heterogeneity in study designs, outcomes measures, and clinical contexts across the included literature, precluding quantitative synthesis or direct comparison of individual techniques. Additionally, several recommendations are based on expert opinion or limited evidence.

conclusionA multimodal approach using both technical refinements and adjunctive measures can make local anesthetic administration less painful. Dermatologists may routinely implement these strategies to improve patient experience and satisfaction.

Indexed as

Anesthesia, LocalAnesthetics, LocalPainPain ManagementProcedural PainHumansLidocainePain MeasurementPatient SatisfactionAnesthetics, LocalLidocaineAnesthesia, localAnestheticInjectionsLidocainePainReview

Identifiers

PMID42107926
PMCPMC13187960

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.