Rare pediatric multi-system thrombosis post-COVID-19: a three-year follow-up case report and narrative review on rivaroxaban for long-term management.

Shiyi Zhu, Xiaozhong Li, Ruyue Chen, Shuang Wu, Lu Jiang, Mengxia Li, Luyao Huang, Ningxun Cui

Abstract readCase ReportsReview

In one paragraph

Review in Orphanet journal of rare diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shiyi ZhuDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Soochow, 215000, China.

Xiaozhong LiDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Soochow, 215000, China.

Ruyue ChenDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Soochow, 215000, China.

Shuang WuDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Soochow, 215000, China.

Lu JiangDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Soochow, 215000, China.

Mengxia LiDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Soochow, 215000, China.

Luyao HuangDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Soochow, 215000, China.

Ningxun CuiDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Soochow, 215000, China. cuiningxun@126.com.ORCID http://orcid.org/0009-0008-0590-9359

Funding

Key Laboratory in Science and Technology Development Project of Suzhou SS202067Key Laboratory in Science and Technology Development Project of Suzhou SZXK202106

6 · The paper itself

Abstract

This retrospective study presents a 10-year-old male with multi-systemic venous thromboembolism (VTE) secondary to COVID-19, including right ventricular thrombus(40 mm × 18 mm), bilateral iliac vein thrombosis, pulmonary embolism, and renal vein thrombosis. The child presented with fever, abdominal pain, and elevated inflammatory markers (CRP 222.72 mg/L, WBC 22.41 × 10

Indexed as

COVID-19Factor Xa InhibitorsRivaroxabanThrombosisVenous ThromboembolismAnticoagulantsChildFollow-Up StudiesHumansMalePulmonary EmbolismRetrospective StudiesSARS-CoV-2AnticoagulantsFactor Xa InhibitorsRivaroxabanCOVID-19Pediatric anticoagulationRivaroxabanThrombosisVenous thromboembolism

Identifiers

PMID42106851

DOI10.1186/s13023-026-04382-7

PMCPMC13335362

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.