Evidence map›Paper›PMID 42106745›Full record

ArticleJournal of orthopaedic surgery and research2026

Biomechanical advantage of anterior over central cage placement in XLIF with bilateral pedicle screw fixation: a finite element analysis.

Liang Wu, Jingxuan Feng, Ruijue Zhu, Peng Cui, Wei Zhang, Guangbao Li, Shenghui Huang, Xianhua Cai, Wenbin Wu, Lei He

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Article in Journal of orthopaedic surgery and research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

10 authors.

Liang Wu *Department of Spine Surgery, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Jingxuan Feng *Department of Spine Surgery, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Ruijue Zhu *Department of Spine Surgery, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Peng CuiDepartment of Orthopaedics, South China Hospital, Shenzhen University, Shenzhen, China.
Wei ZhangDepartment of Orthopaedics, South China Hospital, Shenzhen University, Shenzhen, China.
Guangbao LiDepartment of Orthopaedics, South China Hospital, Shenzhen University, Shenzhen, China.
Shenghui HuangDepartment of Orthopaedics, South China Hospital, Shenzhen University, Shenzhen, China.
Xianhua CaiDepartment of Orthopaedics, South China Hospital, Shenzhen University, Shenzhen, China.
Wenbin WuDepartment of Spine Surgery, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China. wuwb25@mail.sysu.edu.cn.
Lei HeDepartment of Spine Surgery, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China. helei26@mail.sysu.edu.cn.

Funding

The Third Affiliated Hospital of Sun Yat-sen University YHJH202405
6 · The paper itself

Abstract

objectiveThis finite element study aimed to compare the biomechanical differences between anterior and central cage placement in L3-L4 XLIF supplemented with bilateral pedicle screw fixation, to evaluate the biomechanical impact of cage positioning on minimizing cage subsidence risk.

methodsThree L1-L5 finite element models were developed from healthy volunteer CT data: intact (Group A), L3-L4 XLIF with anterior cage placement (Group B), and central cage placement (Group C). Loads simulating flexion, extension, lateral bending, and rotation were applied. Segmental stability and cage stress distribution were analyzed.

resultsBoth surgical groups markedly decreased range of motion (ROM) at L3-L4 compared to Group A. The peak stress on the cage was consistently lower in Group B than in Group C across all motions. The screw-rod system stress in Group B was higher than in Group C in all motions except flexion. Facet joint stress in adjacent segments was higher in Group C than in Groups A and B.

conclusionIn this finite element model, anterior cage placement was associated with lower cage stress and higher posterior instrumentation stress than central placement, while segmental stability remained similar. These results indicate a different load-sharing pattern and suggest potential biomechanical differences in adjacent segment loading. Further research is needed to clarify the clinical implications.

Indexed as

Finite Element AnalysisLumbar VertebraePedicle ScrewsSpinal FusionAdultBiomechanical PhenomenaFemaleHumansMaleRange of Motion, ArticularBiomechanicsCage SubsidenceExtreme Lateral Interbody Fusion (XLIF)Finite Element Analysis

Identifiers

PMID42106745
PMCPMC13366600

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