ArticleBMC medical imaging2026
Recovery of thalamic damage after decompression by
Article in BMC medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundTo access the changes of thalamic metabolites before and after surgery in patients with Cervical Spondylotic Myelopathy (CSM) using Hydrogen Proton Magnetic Resonance Spectroscopy (
methodsForty-eight CSM patients who underwent cervical decompression surgery from December 2022 to June 2023 were included, and 33 healthy volunteers were recruited. All subjects underwent bilateral thalamic
resultsResults Compared to the HCs, patients with CSM showed significantly pre- and post-operative NAA/Cr (t = -4.988, P < 0.001; t = -3.562, P = 0.001), Cho/Cr (t = -5.946, P < 0.001; t = -2.764, P = 0.007), mI/Cr (t = -3.988, P < 0.001; t = -2.079, P = 0.041) and FA (t = -4.884, P < 0.001; t = -3.813, P < 0.001). There was no difference in Glx/Cr and ADC between patients in patients with CSM, either preoperatively or postoperatively, compared to HCs. Post-operative NAA/Cr (t = -2.805, P = 0.007), mI/Cr (t = -3.285, P = 0.003) and FA (t = -2.690, P = 0.007) were increased in CSM patients compared to pre-operative NAA/Cr and mI/Cr. In CSM patients, ΔmI/Cr correlated significantly with ΔmJOA (r = 0.4782, P < 0.001).
conclusionThe preliminary findings indicate that metabolites in the thalamus of CSM patients exhibit changes following surgery. Additionally, it has been demonstrated that elevated post operiative mI correlates with improvements in neurological function.
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