Evidence map›Paper›PMID 42106650›Full record

Observational studyBMC pediatrics2026

Growth patterns in coeliac disease - a longitudinal study of children aged 0-6 years in Sweden.

Lisa Andersson Fjelstad, Annelie Lindholm, Julia S Malmborg, Awais Ashfaq, Lars Gelander, Anton Holmgren

Abstract readObservational Study
In one paragraph

Observational study in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lisa Andersson FjelstadSchool of Health and Welfare, Halmstad University, Halmstad, Sweden.ORCID 0009-0003-8231-0861
Annelie LindholmSchool of Health and Welfare, Halmstad University, Halmstad, Sweden.ORCID 0000-0003-4451-1593
Julia S MalmborgSchool of Health and Welfare, Halmstad University, Halmstad, Sweden.ORCID 0000-0001-9918-461X
Awais AshfaqDepartment of Research and Development, Region Halland, Halmstad, Sweden.ORCID 0000-0001-5688-0156
Lars GelanderDepartment of Paediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0003-1728-4014
Anton HolmgrenDepartment of Research and Development, Region Halland, Halmstad, Sweden. Anton.Holmgren@regionhalland.se.ORCID 0000-0003-0940-8726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAssociations between growth deviations and coeliac disease (CD) in children have been documented, but longitudinal evidence-particularly concerning when such deviations first emerge-is limited. The aim of this study was to investigate the occurrence and timing of growth deviations in relation to CD diagnosis, and to assess whether these patterns differed between boys and girls in a Swedish preschool population.

methodsThis retrospective longitudinal study was conducted as part of the project Evidence based knowledge about deviant growth in children 0-6 years. A total of 185 children with CD were identified through the Regional Healthcare Information Platform. Background characteristics and growth deviations relative to the time of CD diagnosis were analysed using descriptive statistics and tests, including chi square, Mann-Whitney U, one way ANOVA, Kruskal-Wallis, paired t tests, and Wilcoxon signed rank tests.

resultsOf the 185 participating children, 64 (34.6%) were boys and 121 (65.4%) were girls. Growth deviations were most pronounced at the time of diagnosis, with mean weight SDS of - 0.54 (± 1.2) and mean height SDS of - 0.48 (± 1.1). No significant sex differences were observed. Children diagnosed between 36 and 48 months exhibited significantly greater negative height SDS deviations at one year and six months prior to diagnosis compared with younger age groups. Significant improvements in both weight SDS and height SDS were observed during the two years following diagnosis and initiation of treatment.

conclusionGrowth deviations varied according to age at CD diagnosis, with the most pronounced deviations occurring in proximity to the diagnostic timepoint. Growth improved significantly during the two years following diagnosis. These findings suggest that subtle growth deviations may be detectable years before diagnosis, supporting the clinical value of careful growth monitoring in paediatric care. Further research on the implementation of growth based screening parameters in routine practice is warranted.

Indexed as

Body HeightBody WeightCeliac DiseaseGrowth DisordersAge FactorsAnalysis of VarianceChildChild, PreschoolFemaleHumansInfantInfant, NewbornLongitudinal StudiesMaleRetrospective StudiesSex FactorsCatch-up growthCoeliac diseaseGrowth deviationHealthcarePaediatric care

Identifiers

PMID42106650
PMCPMC13159342

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.