ArticleBMC pregnancy and childbirth2026
Correlation of low birth weight with infertility and ART treatment: single-center cohort analysis of 7697 singleton live births.
Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundLow birth weight (LBW) significantly influences neonatal prognosis as well as growth and development in adult. This study aimed to explore the increased risk of low birth weight (LBW) in singleton live births in connection with infertility treatment is attributed to patient- and cycle-dependent factors related to infertility or the use of ART procedures.
methodsThis was a retrospective cohort study of 7697 patients with singleton live births of IVF/ICSI treatment between January 2016 and December 2020. We explored the increased risk of LBW and patient- and cycle-dependent factors to determine their influence on the likelihood of LBW. To analyze this relationship, we employed both univariate and multivariate logistic regression analyses.
resultsLBW occurred in 5.81% out of 7697 singleton live births. The body mass index (BMI), endometrial thickness (EMT), number of transferred embryos, and vanishing multiple pregnancies were significantly associated with the LBW rate according to the univariate logistic regression analysis. After adjusting for confounding factors, overweight (BMI 24-27.9 kg/m
conclusionsMaternal BMI, EMT, and vanishing multiple pregnancies are important risk factors for LBW in single infants conceived through IVF. It is essential to consider pre-pregnancy maternal weight, endometrial thickness, and promote the practice of elective single embryo transfer .
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